Specimen illumination apparatus with optical cavity for dark field illumination
Abstract
An illumination apparatus with a specimen slide holder, an illumination source, an optical cavity producing multiple reflection of illumination light to a specimen comprising a first and a second reflective surface arranged to achieve multiple reflections of light to a specimen is provided. The apparatus can further include additional reflective surfaces to achieve the optical cavity, a slide for mounting the specimen, a coverslip which is a reflective component of the optical cavity, one or more prisms for directing light within the optical cavity, antifading solutions for improving the viewing properties of the specimen, an array of materials for analysis, fluorescent components, curved reflective surfaces as components of the optical cavity, specimen detection apparatus, optical detection equipment, computers for analysis of optical images, a plane polarizer, fiberoptics, light transmission apertures, microscopic components, lenses for viewing the specimen, and upper and lower mirrors above and below the specimen slide as components of the optical cavity. Methods of using the apparatus are also provided.
- Inventors:
-
- Walnut Creek, CA
- Lafayette, CA
- Issue Date:
- Research Org.:
- Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
- OSTI Identifier:
- 872657
- Patent Number(s):
- 5982534
- Assignee:
- Regents of University of California (Oakland, CA)
- Patent Classifications (CPCs):
-
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
G - PHYSICS G02 - OPTICS G02B - OPTICAL ELEMENTS, SYSTEMS, OR APPARATUS
- DOE Contract Number:
- W-7405-ENG-48
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- specimen; illumination; apparatus; optical; cavity; dark; field; slide; holder; source; producing; multiple; reflection; light; comprising; reflective; surface; arranged; achieve; reflections; provided; additional; surfaces; mounting; coverslip; component; prisms; directing; antifading; solutions; improving; viewing; properties; array; materials; analysis; fluorescent; components; curved; detection; equipment; computers; images; plane; polarizer; fiberoptics; transmission; apertures; microscopic; lenses; upper; mirrors; below; methods; optical detection; light transmission; multiple reflections; detection apparatus; illumination source; optical cavity; reflective surface; reflective surfaces; producing multiple; optical image; optical images; directing light; specimen comprising; curved reflective; detection equipment; illumination light; illumination apparatus; multiple reflection; dark field; /359/422/435/999/
Citation Formats
Pinkel, Daniel, Sudar, Damir, and Albertson, Donna. Specimen illumination apparatus with optical cavity for dark field illumination. United States: N. p., 1999.
Web.
Pinkel, Daniel, Sudar, Damir, & Albertson, Donna. Specimen illumination apparatus with optical cavity for dark field illumination. United States.
Pinkel, Daniel, Sudar, Damir, and Albertson, Donna. Fri .
"Specimen illumination apparatus with optical cavity for dark field illumination". United States. https://www.osti.gov/servlets/purl/872657.
@article{osti_872657,
title = {Specimen illumination apparatus with optical cavity for dark field illumination},
author = {Pinkel, Daniel and Sudar, Damir and Albertson, Donna},
abstractNote = {An illumination apparatus with a specimen slide holder, an illumination source, an optical cavity producing multiple reflection of illumination light to a specimen comprising a first and a second reflective surface arranged to achieve multiple reflections of light to a specimen is provided. The apparatus can further include additional reflective surfaces to achieve the optical cavity, a slide for mounting the specimen, a coverslip which is a reflective component of the optical cavity, one or more prisms for directing light within the optical cavity, antifading solutions for improving the viewing properties of the specimen, an array of materials for analysis, fluorescent components, curved reflective surfaces as components of the optical cavity, specimen detection apparatus, optical detection equipment, computers for analysis of optical images, a plane polarizer, fiberoptics, light transmission apertures, microscopic components, lenses for viewing the specimen, and upper and lower mirrors above and below the specimen slide as components of the optical cavity. Methods of using the apparatus are also provided.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1999},
month = {1}
}
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