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Title: Specimen illumination apparatus with optical cavity for dark field illumination

Abstract

An illumination apparatus with a specimen slide holder, an illumination source, an optical cavity producing multiple reflection of illumination light to a specimen comprising a first and a second reflective surface arranged to achieve multiple reflections of light to a specimen is provided. The apparatus can further include additional reflective surfaces to achieve the optical cavity, a slide for mounting the specimen, a coverslip which is a reflective component of the optical cavity, one or more prisms for directing light within the optical cavity, antifading solutions for improving the viewing properties of the specimen, an array of materials for analysis, fluorescent components, curved reflective surfaces as components of the optical cavity, specimen detection apparatus, optical detection equipment, computers for analysis of optical images, a plane polarizer, fiberoptics, light transmission apertures, microscopic components, lenses for viewing the specimen, and upper and lower mirrors above and below the specimen slide as components of the optical cavity. Methods of using the apparatus are also provided.

Inventors:
 [1];  [1];  [2]
  1. (Walnut Creek, CA)
  2. (Lafayette, CA)
Issue Date:
Research Org.:
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
OSTI Identifier:
872657
Patent Number(s):
5982534
Assignee:
Regents of University of California (Oakland, CA) LLNL
DOE Contract Number:  
W-7405-ENG-48
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
specimen; illumination; apparatus; optical; cavity; dark; field; slide; holder; source; producing; multiple; reflection; light; comprising; reflective; surface; arranged; achieve; reflections; provided; additional; surfaces; mounting; coverslip; component; prisms; directing; antifading; solutions; improving; viewing; properties; array; materials; analysis; fluorescent; components; curved; detection; equipment; computers; images; plane; polarizer; fiberoptics; transmission; apertures; microscopic; lenses; upper; mirrors; below; methods; optical detection; light transmission; multiple reflections; detection apparatus; illumination source; optical cavity; reflective surface; reflective surfaces; producing multiple; optical image; optical images; directing light; specimen comprising; curved reflective; detection equipment; illumination light; illumination apparatus; multiple reflection; dark field; /359/422/435/999/

Citation Formats

Pinkel, Daniel, Sudar, Damir, and Albertson, Donna. Specimen illumination apparatus with optical cavity for dark field illumination. United States: N. p., 1999. Web.
Pinkel, Daniel, Sudar, Damir, & Albertson, Donna. Specimen illumination apparatus with optical cavity for dark field illumination. United States.
Pinkel, Daniel, Sudar, Damir, and Albertson, Donna. Fri . "Specimen illumination apparatus with optical cavity for dark field illumination". United States. https://www.osti.gov/servlets/purl/872657.
@article{osti_872657,
title = {Specimen illumination apparatus with optical cavity for dark field illumination},
author = {Pinkel, Daniel and Sudar, Damir and Albertson, Donna},
abstractNote = {An illumination apparatus with a specimen slide holder, an illumination source, an optical cavity producing multiple reflection of illumination light to a specimen comprising a first and a second reflective surface arranged to achieve multiple reflections of light to a specimen is provided. The apparatus can further include additional reflective surfaces to achieve the optical cavity, a slide for mounting the specimen, a coverslip which is a reflective component of the optical cavity, one or more prisms for directing light within the optical cavity, antifading solutions for improving the viewing properties of the specimen, an array of materials for analysis, fluorescent components, curved reflective surfaces as components of the optical cavity, specimen detection apparatus, optical detection equipment, computers for analysis of optical images, a plane polarizer, fiberoptics, light transmission apertures, microscopic components, lenses for viewing the specimen, and upper and lower mirrors above and below the specimen slide as components of the optical cavity. Methods of using the apparatus are also provided.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1999},
month = {1}
}

Patent:

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