Method of Identifying a Base in a Nucleic Acid
Abstract
Devices and techniques for hybridization of nucleic acids and for determining the sequence of nucleic acids. Arrays of nucleic acids are formed by techniques, preferably high resolution, light-directed techniques. Positions of hybridization of a target nucleic acid are determined by, e.g., epifluorescence microscopy. Devices and techniques are proposed to determine the sequence of a target nucleic acid more efficiently and more quickly through such synthesis and detection techniques.
- Inventors:
-
- Palo Alto, CA
- Mt. View, CA
- Issue Date:
- Research Org.:
- Affymax Research Institute
- OSTI Identifier:
- 872594
- Patent Number(s):
- 5968740
- Assignee:
- Affymetrix, Inc. (Santa Clara, CA)
- Patent Classifications (CPCs):
-
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01J - CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY
B - PERFORMING OPERATIONS B82 - NANOTECHNOLOGY B82Y - SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES
- DOE Contract Number:
- FG03-92ER81275
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- method; identifying; base; nucleic; acid; devices; techniques; hybridization; acids; determining; sequence; arrays; formed; preferably; resolution; light-directed; positions; target; determined; epifluorescence; microscopy; proposed; determine; efficiently; quickly; synthesis; detection; detection techniques; nucleic acid; nucleic acids; target nucleic; epifluorescence microscopy; light-directed techniques; target nuclei; /435/999/
Citation Formats
Fodor, Stephen P. A., Lipshutz, Robert J, and Huang, Xiaohua. Method of Identifying a Base in a Nucleic Acid. United States: N. p., 1999.
Web.
Fodor, Stephen P. A., Lipshutz, Robert J, & Huang, Xiaohua. Method of Identifying a Base in a Nucleic Acid. United States.
Fodor, Stephen P. A., Lipshutz, Robert J, and Huang, Xiaohua. Fri .
"Method of Identifying a Base in a Nucleic Acid". United States. https://www.osti.gov/servlets/purl/872594.
@article{osti_872594,
title = {Method of Identifying a Base in a Nucleic Acid},
author = {Fodor, Stephen P. A. and Lipshutz, Robert J and Huang, Xiaohua},
abstractNote = {Devices and techniques for hybridization of nucleic acids and for determining the sequence of nucleic acids. Arrays of nucleic acids are formed by techniques, preferably high resolution, light-directed techniques. Positions of hybridization of a target nucleic acid are determined by, e.g., epifluorescence microscopy. Devices and techniques are proposed to determine the sequence of a target nucleic acid more efficiently and more quickly through such synthesis and detection techniques.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1999},
month = {1}
}
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