skip to main content
DOE Patents title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Electro-osmotically driven liquid delivery method and apparatus

Abstract

Method and apparatus for controlling precisely the composition and delivery of liquid at sub-.mu.L/min flow rate. One embodiment of such a delivery system is an electro-osmotically driven gradient flow delivery system that generates dynamic gradient flows with sub-.mu.L/min flow rates by merging a plurality of electro-osmotic flows. These flows are delivered by a plurality of delivery arms attached to a mixing connector, where they mix and then flow into a receiving means, preferably a column. Each inlet of the plurality of delivery arms is placed in a corresponding solution reservoir. A plurality of independent programmable high-voltage power supplies is used to apply a voltage program to each of the plurality of solution reservoirs to regulate the electro-osmotic flow in each delivery arm. The electro-osmotic flow rates in the delivery arms are changed with time according to each voltage program to deliver the required gradient profile to the column.

Inventors:
 [1];  [2];  [3];  [4];  [4]
  1. Fremont, CA
  2. Livermore, CA
  3. Pleasanton, CA
  4. Stanford, CA
Issue Date:
Research Org.:
Sandia National Laboratories (SNL), Albuquerque, NM, and Livermore, CA (United States)
OSTI Identifier:
872464
Patent Number(s):
5942093
Assignee:
Sandia Corporation (Livermore, CA)
Patent Classifications (CPCs):
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
DOE Contract Number:  
AC04-94AL85000
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
electro-osmotically; driven; liquid; delivery; method; apparatus; controlling; precisely; composition; sub-; flow; rate; embodiment; gradient; generates; dynamic; flows; rates; merging; plurality; electro-osmotic; delivered; arms; attached; mixing; connector; mix; receiving; means; preferably; column; inlet; placed; corresponding; solution; reservoir; independent; programmable; high-voltage; power; supplies; apply; voltage; reservoirs; regulate; arm; changed; time; according; deliver; required; profile; voltage power; flow rates; flow rate; receiving means; power supplies; electro-osmotic flow; liquid delivery; electro-osmotically driven; /204/

Citation Formats

Rakestraw, David J, Anex, Deon S, Yan, Chao, Dadoo, Rajeev, and Zare, Richard N. Electro-osmotically driven liquid delivery method and apparatus. United States: N. p., 1999. Web.
Rakestraw, David J, Anex, Deon S, Yan, Chao, Dadoo, Rajeev, & Zare, Richard N. Electro-osmotically driven liquid delivery method and apparatus. United States.
Rakestraw, David J, Anex, Deon S, Yan, Chao, Dadoo, Rajeev, and Zare, Richard N. Fri . "Electro-osmotically driven liquid delivery method and apparatus". United States. https://www.osti.gov/servlets/purl/872464.
@article{osti_872464,
title = {Electro-osmotically driven liquid delivery method and apparatus},
author = {Rakestraw, David J and Anex, Deon S and Yan, Chao and Dadoo, Rajeev and Zare, Richard N},
abstractNote = {Method and apparatus for controlling precisely the composition and delivery of liquid at sub-.mu.L/min flow rate. One embodiment of such a delivery system is an electro-osmotically driven gradient flow delivery system that generates dynamic gradient flows with sub-.mu.L/min flow rates by merging a plurality of electro-osmotic flows. These flows are delivered by a plurality of delivery arms attached to a mixing connector, where they mix and then flow into a receiving means, preferably a column. Each inlet of the plurality of delivery arms is placed in a corresponding solution reservoir. A plurality of independent programmable high-voltage power supplies is used to apply a voltage program to each of the plurality of solution reservoirs to regulate the electro-osmotic flow in each delivery arm. The electro-osmotic flow rates in the delivery arms are changed with time according to each voltage program to deliver the required gradient profile to the column.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1999},
month = {1}
}

Patent:

Save / Share: