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Title: Low density lipoprotein fraction assay for cardiac disease risk

Abstract

A variable rate density gradient electrophoric gel is described which separate LDL subfractions with the precision of ultracentrifugation techniques. Also, an innovative bottom inlet mixing chamber particularly useful for producing these gels is described.

Inventors:
 [1];  [1];  [2]
  1. Berkeley, CA
  2. San Pablo, CA
Issue Date:
Research Org.:
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
OSTI Identifier:
872393
Patent Number(s):
5925229
Assignee:
Regents of University of California (Oakland, CA)
Patent Classifications (CPCs):
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
DOE Contract Number:  
AC03-76SF00098
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
density; lipoprotein; fraction; assay; cardiac; disease; risk; variable; rate; gradient; electrophoric; described; separate; ldl; subfractions; precision; ultracentrifugation; techniques; innovative; bottom; inlet; mixing; chamber; particularly; useful; producing; gels; particularly useful; mixing chamber; density gradient; variable rate; density lipoprotein; /204/

Citation Formats

Krauss, Ronald M, Blanche, Patricia J, and Orr, Joseph. Low density lipoprotein fraction assay for cardiac disease risk. United States: N. p., 1999. Web.
Krauss, Ronald M, Blanche, Patricia J, & Orr, Joseph. Low density lipoprotein fraction assay for cardiac disease risk. United States.
Krauss, Ronald M, Blanche, Patricia J, and Orr, Joseph. Fri . "Low density lipoprotein fraction assay for cardiac disease risk". United States. https://www.osti.gov/servlets/purl/872393.
@article{osti_872393,
title = {Low density lipoprotein fraction assay for cardiac disease risk},
author = {Krauss, Ronald M and Blanche, Patricia J and Orr, Joseph},
abstractNote = {A variable rate density gradient electrophoric gel is described which separate LDL subfractions with the precision of ultracentrifugation techniques. Also, an innovative bottom inlet mixing chamber particularly useful for producing these gels is described.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1999},
month = {1}
}

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Works referenced in this record:

Production of polyacrylamide gradient gels for the electrophoretic resolution of lipoproteins.
journal, December 1992


Detection and quantitation of LDL subfractions
journal, January 1992


Identification of multiple subclasses of plasma low density lipoproteins in normal humans.
journal, January 1982


Correlations of plasma lipoproteins with LDL subfractions by particle size in men and women.
journal, May 1992


Low-density lipoprotein subclasses and risk of coronary artery disease
journal, January 1991


Effect of Diabetes on Lipoprotein Size
journal, November 1995