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Title: Laser vaporization/ionization interface for coupling microscale separation techniques with mass spectrometry

Abstract

The present invention provides a laser-induced vaporization and ionization interface for directly coupling microscale separation processes to a mass spectrometer. Vaporization and ionization of the separated analytes are facilitated by the addition of a light-absorbing component to the separation buffer or solvent.

Inventors:
 [1];  [2]
  1. Ames, IA
  2. Taichung Hsien, TW
Issue Date:
Research Org.:
Ames Lab., Ames, IA (United States); Iowa State Univ., Ames, IA (United States)
OSTI Identifier:
872359
Patent Number(s):
5917185
Application Number:
08/882,855
Assignee:
Iowa State University Research Foundation, Inc. (Ames, IA)
Patent Classifications (CPCs):
H - ELECTRICITY H01 - BASIC ELECTRIC ELEMENTS H01J - ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
DOE Contract Number:  
W-7405-ENG-82
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
laser; vaporization; ionization; interface; coupling; microscale; separation; techniques; mass; spectrometry; provides; laser-induced; directly; processes; spectrometer; separated; analytes; facilitated; addition; light-absorbing; component; buffer; solvent; separation processes; separation techniques; separation process; mass spectrometer; mass spectrometry; absorbing component; microscale separation; ionization interface; separation technique; scale separation; directly coupling; laser vaporization; coupling microscale; /250/

Citation Formats

Yeung, Edward S, and Chang, Yu-chen. Laser vaporization/ionization interface for coupling microscale separation techniques with mass spectrometry. United States: N. p., 1999. Web.
Yeung, Edward S, & Chang, Yu-chen. Laser vaporization/ionization interface for coupling microscale separation techniques with mass spectrometry. United States.
Yeung, Edward S, and Chang, Yu-chen. Fri . "Laser vaporization/ionization interface for coupling microscale separation techniques with mass spectrometry". United States. https://www.osti.gov/servlets/purl/872359.
@article{osti_872359,
title = {Laser vaporization/ionization interface for coupling microscale separation techniques with mass spectrometry},
author = {Yeung, Edward S and Chang, Yu-chen},
abstractNote = {The present invention provides a laser-induced vaporization and ionization interface for directly coupling microscale separation processes to a mass spectrometer. Vaporization and ionization of the separated analytes are facilitated by the addition of a light-absorbing component to the separation buffer or solvent.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1999},
month = {1}
}

Patent:

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