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Title: Microfabricated therapeutic actuators

Abstract

Microfabricated therapeutic actuators are fabricated using a shape memory polymer (SMP), a polyurethane-based material that undergoes a phase transformation at a specified temperature (Tg). At a temperature above temperature Tg material is soft and can be easily reshaped into another configuration. As the temperature is lowered below temperature Tg the new shape is fixed and locked in as long as the material stays below temperature Tg. Upon reheating the material to a temperature above Tg, the material will return to its original shape. By the use of such SMP material, SMP microtubing can be used as a release actuator for the delivery of embolic coils through catheters into aneurysms, for example. The microtubing can be manufactured in various sizes and the phase change temperature Tg is determinate for an intended temperature target and intended use.

Inventors:
 [1];  [2];  [3];  [4];  [3]
  1. Walnut Creek, CA
  2. Berkeley, CA
  3. Livermore, CA
  4. Pleasanton, CA
Issue Date:
Research Org.:
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
OSTI Identifier:
872326
Patent Number(s):
5911737
Assignee:
Regents of University of California (Oakland, CA)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS
DOE Contract Number:  
W-7405-ENG-48
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
microfabricated; therapeutic; actuators; fabricated; shape; memory; polymer; smp; polyurethane-based; material; undergoes; phase; transformation; specified; temperature; tg; soft; easily; reshaped; configuration; lowered; below; fixed; locked; stays; reheating; return; original; microtubing; release; actuator; delivery; embolic; coils; catheters; aneurysms; example; manufactured; various; sizes; change; determinate; intended; target; various sizes; below temperature; phase transformation; original shape; microfabricated therapeutic; smp microtubing; therapeutic actuators; temperature tg; phase change; shape memory; specified temperature; memory polymer; release actuator; tg material; temperature target; stays below; polyurethane-based material; change temperature; smp material; embolic coils; embolic coil; lowered below; material stays; easily reshaped; intended temperature; therapeutic actuator; /606/128/

Citation Formats

Lee, Abraham P, Northrup, M Allen, Ciarlo, Dino R, Krulevitch, Peter A, and Benett, William J. Microfabricated therapeutic actuators. United States: N. p., 1999. Web.
Lee, Abraham P, Northrup, M Allen, Ciarlo, Dino R, Krulevitch, Peter A, & Benett, William J. Microfabricated therapeutic actuators. United States.
Lee, Abraham P, Northrup, M Allen, Ciarlo, Dino R, Krulevitch, Peter A, and Benett, William J. Fri . "Microfabricated therapeutic actuators". United States. https://www.osti.gov/servlets/purl/872326.
@article{osti_872326,
title = {Microfabricated therapeutic actuators},
author = {Lee, Abraham P and Northrup, M Allen and Ciarlo, Dino R and Krulevitch, Peter A and Benett, William J},
abstractNote = {Microfabricated therapeutic actuators are fabricated using a shape memory polymer (SMP), a polyurethane-based material that undergoes a phase transformation at a specified temperature (Tg). At a temperature above temperature Tg material is soft and can be easily reshaped into another configuration. As the temperature is lowered below temperature Tg the new shape is fixed and locked in as long as the material stays below temperature Tg. Upon reheating the material to a temperature above Tg, the material will return to its original shape. By the use of such SMP material, SMP microtubing can be used as a release actuator for the delivery of embolic coils through catheters into aneurysms, for example. The microtubing can be manufactured in various sizes and the phase change temperature Tg is determinate for an intended temperature target and intended use.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1999},
month = {1}
}

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