Method of making L-dopa from L-tyrosine
Abstract
The invention is a method of making a L-dopa from L-tyrosine in the presence of an enzyme catalyst and oxygen. By starting with L-tyrosine, no variant of the L-dopa is produced and the L-dopa is stable in the presence of the enzyme catalyst. In other words, the reaction favors the L-dopa and is not reversible.
- Inventors:
-
- Richland, WA
- Taejon, KR
- Issue Date:
- Research Org.:
- Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
- OSTI Identifier:
- 871977
- Patent Number(s):
- 5837504
- Assignee:
- Battelle Memorial Institute (Richland, WA); Washington State University Research Foundation (Pullman, WA)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
- DOE Contract Number:
- AC06-76RL01830
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- method; l-dopa; l-tyrosine; presence; enzyme; catalyst; oxygen; starting; variant; produced; stable; words; reaction; favors; reversible; enzyme catalyst; /435/
Citation Formats
Xun, Luying, and Lee, Jang Young. Method of making L-dopa from L-tyrosine. United States: N. p., 1998.
Web.
Xun, Luying, & Lee, Jang Young. Method of making L-dopa from L-tyrosine. United States.
Xun, Luying, and Lee, Jang Young. Thu .
"Method of making L-dopa from L-tyrosine". United States. https://www.osti.gov/servlets/purl/871977.
@article{osti_871977,
title = {Method of making L-dopa from L-tyrosine},
author = {Xun, Luying and Lee, Jang Young},
abstractNote = {The invention is a method of making a L-dopa from L-tyrosine in the presence of an enzyme catalyst and oxygen. By starting with L-tyrosine, no variant of the L-dopa is produced and the L-dopa is stable in the presence of the enzyme catalyst. In other words, the reaction favors the L-dopa and is not reversible.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1998},
month = {1}
}