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Title: Cell-targeted lytic pore-forming agents

Abstract

A chimeric compound that contains a cell-specific ligand linked to a pore-forming agent capable of lysing a cell.

Inventors:
 [1];  [2]
  1. Grafton, MA
  2. Auburn, MA
Issue Date:
Research Org.:
Worcester Foundation
OSTI Identifier:
871879
Patent Number(s):
5817771
Assignee:
Worcester Foundation for Experimental Biology (Shrewsbury, MA)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61P - SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
DOE Contract Number:  
FG02-90ER20018
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
cell-targeted; lytic; pore-forming; agents; chimeric; compound; contains; cell-specific; ligand; linked; agent; capable; lysing; cell; agent capable; pore-forming agents; pore-forming agent; chimeric compound; cell-specific ligand; ligand linked; forming agent; cell-targeted lytic; lytic pore-forming; /530/435/

Citation Formats

Bayley, Hagen, and Walker, Barbara J. Cell-targeted lytic pore-forming agents. United States: N. p., 1998. Web.
Bayley, Hagen, & Walker, Barbara J. Cell-targeted lytic pore-forming agents. United States.
Bayley, Hagen, and Walker, Barbara J. Thu . "Cell-targeted lytic pore-forming agents". United States. https://www.osti.gov/servlets/purl/871879.
@article{osti_871879,
title = {Cell-targeted lytic pore-forming agents},
author = {Bayley, Hagen and Walker, Barbara J},
abstractNote = {A chimeric compound that contains a cell-specific ligand linked to a pore-forming agent capable of lysing a cell.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Thu Jan 01 00:00:00 EST 1998},
month = {Thu Jan 01 00:00:00 EST 1998}
}

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A Pore-forming protein with a protease-activated trigger
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Staphylococcal alpha toxin — recent advances
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Problems in the investigational study and clinical use of cancer immunotherapy
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