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Title: Processing of hydroxylapatite coatings on titanium alloy bone prostheses

Abstract

Processing of hydroxylapatite sol-gel films on titanium alloy bone prostheses. A method utilizing non-line-of-sight ion beam implantation and/or rapid thermal processing to provide improved bonding of layers of hydroxylapatite to titanium alloy substrates while encouraging bone ingrowth into the hydroxylapatite layers located away from the substrate, is described for the fabrication of prostheses. The first layer of hydroxylapatite is mixed into the substrate by the ions or rapidly thermally annealed, while subsequent layers are heat treated or densified using ion implantation to form layers of decreasing density and larger crystallization, with the outermost layers being suitable for bone ingrowth.

Inventors:
 [1];  [2];  [3];  [3]
  1. Espanola, NM
  2. Santa Clara, CA
  3. Phoenix, AZ
Issue Date:
Research Org.:
Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
OSTI Identifier:
871877
Patent Number(s):
5817326
Assignee:
Regents of University of California (Los Alamos, NM)
Patent Classifications (CPCs):
C - CHEMISTRY C23 - COATING METALLIC MATERIAL C23C - COATING METALLIC MATERIAL
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61F - FILTERS IMPLANTABLE INTO BLOOD VESSELS
DOE Contract Number:  
W-7405-ENG-36
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
processing; hydroxylapatite; coatings; titanium; alloy; bone; prostheses; sol-gel; films; method; utilizing; non-line-of-sight; beam; implantation; rapid; thermal; provide; improved; bonding; layers; substrates; encouraging; ingrowth; located; substrate; described; fabrication; layer; mixed; rapidly; thermally; annealed; subsequent; heat; treated; densified; form; decreasing; density; larger; crystallization; outermost; suitable; alloy substrates; titanium alloy; provide improved; heat treated; method utilizing; rapid thermal; thermal processing; alloy substrate; outermost layer; form layers; provide improve; alloy bone; bone prostheses; /424/523/

Citation Formats

Nastasi, Michael A, Levine, Timothy E, Mayer, James W, and Pizziconi, Vincent B. Processing of hydroxylapatite coatings on titanium alloy bone prostheses. United States: N. p., 1998. Web.
Nastasi, Michael A, Levine, Timothy E, Mayer, James W, & Pizziconi, Vincent B. Processing of hydroxylapatite coatings on titanium alloy bone prostheses. United States.
Nastasi, Michael A, Levine, Timothy E, Mayer, James W, and Pizziconi, Vincent B. Thu . "Processing of hydroxylapatite coatings on titanium alloy bone prostheses". United States. https://www.osti.gov/servlets/purl/871877.
@article{osti_871877,
title = {Processing of hydroxylapatite coatings on titanium alloy bone prostheses},
author = {Nastasi, Michael A and Levine, Timothy E and Mayer, James W and Pizziconi, Vincent B},
abstractNote = {Processing of hydroxylapatite sol-gel films on titanium alloy bone prostheses. A method utilizing non-line-of-sight ion beam implantation and/or rapid thermal processing to provide improved bonding of layers of hydroxylapatite to titanium alloy substrates while encouraging bone ingrowth into the hydroxylapatite layers located away from the substrate, is described for the fabrication of prostheses. The first layer of hydroxylapatite is mixed into the substrate by the ions or rapidly thermally annealed, while subsequent layers are heat treated or densified using ion implantation to form layers of decreasing density and larger crystallization, with the outermost layers being suitable for bone ingrowth.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1998},
month = {1}
}

Works referenced in this record:

Ion Mixing of Pulsed Laser Deposited Hydroxylapatite (HA)
journal, January 1994


Rapid thermal processing of zirconia thin films produced by the sol‐gel method
journal, August 1991


Ion-beam-induced densification of sol-gel ceramic thin films
journal, March 1994


Ion Beam Mixing of Titanium Overlayers with Hydroxyapatite Substrates
journal, January 1994


Fracture Mechanics of Functionally Graded Materials
journal, January 1995


Hydroxyapatite coatings by a polymeric route
journal, May 1992


Formation of hydroxyapatite coating on pure titanium substrates by ion beam dynamic mixing
journal, January 1994


Ion-Beam-Induced Densification of Zirconia Sol-Gel Thin Films
journal, May 1993