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Title: Method for generating a crystalline .sup.99 MoO.sub.3 product and the isolation .sup.99m Tc compositions therefrom

Abstract

An improved method for producing .sup.99m Tc compositions. .sup.100 Mo metal is irradiated with photons in a particle (electron) accelerator to produce .sup.99 Mo metal which is dissolved in a solvent. A solvated .sup.99 Mo product is then dried to generate a supply of .sup.99 MoO.sub.3 crystals. The crystals are thereafter heated at a temperature which will sublimate the crystals and form a gaseous mixture containing vaporized .sup.99m TcO.sub.3 and vaporized .sup.99m TcO.sub.2 but will not cause the production of vaporized .sup.99 MoO.sub.3. The mixture is then combined with an oxidizing gas to generate a gaseous stream containing vaporized .sup.99m Tc.sub.2 O.sub.7. Next, the gaseous stream is cooled to a temperature sufficient to convert the vaporized .sup.99m Tc.sub.2 O.sub.7 into a condensed .sup.99m Tc-containing product. The product has high purity levels resulting from the use of reduced temperature conditions and ultrafine crystalline .sup.99 MoO.sub.3 starting materials with segregated .sup.99m Tc compositions therein which avoid the production of vaporized .sup.99 MoO.sub.3 contaminants.

Inventors:
 [1];  [1];  [2];  [1]
  1. Idaho Falls, ID
  2. Blackfoot, ID
Issue Date:
Research Org.:
Idaho National Lab. (INL), Idaho Falls, ID (United States)
OSTI Identifier:
871813
Patent Number(s):
5802438
Assignee:
Lockheed Martin Idaho Technologies Company (Idaho Falls, ID)
Patent Classifications (CPCs):
G - PHYSICS G21 - NUCLEAR PHYSICS G21G - CONVERSION OF CHEMICAL ELEMENTS
DOE Contract Number:  
AC07-94ID13223
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
method; generating; crystalline; 99; moo; product; isolation; 99m; tc; compositions; therefrom; improved; producing; 100; metal; irradiated; photons; particle; electron; accelerator; produce; dissolved; solvent; solvated; dried; generate; supply; crystals; thereafter; heated; temperature; sublimate; form; gaseous; mixture; containing; vaporized; tco; production; combined; oxidizing; gas; stream; cooled; sufficient; convert; condensed; tc-containing; purity; levels; resulting; reduced; conditions; ultrafine; starting; materials; segregated; therein; avoid; contaminants; tc compositions; temperature conditions; oxidizing gas; starting material; gaseous stream; mixture containing; improved method; gaseous mixture; temperature sufficient; stream containing; starting materials; reduced temperature; thereafter heated; fine crystalline; purity levels; containing vapor; /423/376/976/

Citation Formats

Bennett, Ralph G, Christian, Jerry D, Kirkham, Robert J, and Tranter, Troy J. Method for generating a crystalline .sup.99 MoO.sub.3 product and the isolation .sup.99m Tc compositions therefrom. United States: N. p., 1998. Web.
Bennett, Ralph G, Christian, Jerry D, Kirkham, Robert J, & Tranter, Troy J. Method for generating a crystalline .sup.99 MoO.sub.3 product and the isolation .sup.99m Tc compositions therefrom. United States.
Bennett, Ralph G, Christian, Jerry D, Kirkham, Robert J, and Tranter, Troy J. Thu . "Method for generating a crystalline .sup.99 MoO.sub.3 product and the isolation .sup.99m Tc compositions therefrom". United States. https://www.osti.gov/servlets/purl/871813.
@article{osti_871813,
title = {Method for generating a crystalline .sup.99 MoO.sub.3 product and the isolation .sup.99m Tc compositions therefrom},
author = {Bennett, Ralph G and Christian, Jerry D and Kirkham, Robert J and Tranter, Troy J},
abstractNote = {An improved method for producing .sup.99m Tc compositions. .sup.100 Mo metal is irradiated with photons in a particle (electron) accelerator to produce .sup.99 Mo metal which is dissolved in a solvent. A solvated .sup.99 Mo product is then dried to generate a supply of .sup.99 MoO.sub.3 crystals. The crystals are thereafter heated at a temperature which will sublimate the crystals and form a gaseous mixture containing vaporized .sup.99m TcO.sub.3 and vaporized .sup.99m TcO.sub.2 but will not cause the production of vaporized .sup.99 MoO.sub.3. The mixture is then combined with an oxidizing gas to generate a gaseous stream containing vaporized .sup.99m Tc.sub.2 O.sub.7. Next, the gaseous stream is cooled to a temperature sufficient to convert the vaporized .sup.99m Tc.sub.2 O.sub.7 into a condensed .sup.99m Tc-containing product. The product has high purity levels resulting from the use of reduced temperature conditions and ultrafine crystalline .sup.99 MoO.sub.3 starting materials with segregated .sup.99m Tc compositions therein which avoid the production of vaporized .sup.99 MoO.sub.3 contaminants.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1998},
month = {1}
}

Works referenced in this record:

Technetium-99m generators—The available options
journal, October 1982


Study of the purity of 99mTc sublimed from fission 99Mo and the radiation dose from the impurities
journal, January 1974


A review of 99mTc generator technology
journal, October 1982


99mTc Sublimation Generators
journal, January 1987


Large-Scale Production and Distribution of Tc-99m Generators for Medical Use
journal, January 1987


Diffusion of Tc-99m in Neutron Irradiated Molybdenum Trioxide and Its Application to Separation
journal, June 1971