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Title: Recombinant lactobacillus for fermentation of xylose to lactic acid and lactate

Abstract

A recombinant Lactobacillus MONT4 is provided which has been genetically engineered with xylose isomerase and xylulokinase genes from Lactobacillus pentosus to impart to the Lactobacillus MONT4 the ability to ferment lignocellulosic biomass containing xylose to lactic acid.

Inventors:
 [1];  [2];  [3];  [4];  [5]
  1. Golden, CO
  2. Lakewood, CO
  3. Littleton, CO
  4. Boulder, CO
  5. Fort Collins, CO
Issue Date:
Research Org.:
Midwest Research Institute, Kansas City, MO (United States)
OSTI Identifier:
871796
Patent Number(s):
5798237
Assignee:
Midwest Research Institute (Kansas City, MI)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
DOE Contract Number:  
AC36-83CH10093
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
recombinant; lactobacillus; fermentation; xylose; lactic; acid; lactate; mont4; provided; genetically; engineered; isomerase; xylulokinase; genes; pentosus; impart; ability; ferment; lignocellulosic; biomass; containing; xylose isomerase; lactic acid; lignocellulosic biomass; genetically engineered; recombinant lactobacillus; /435/

Citation Formats

Picataggio, Stephen K, Zhang, Min, Franden, Mary Ann, Mc Millan, James D, and Finkelstein, Mark. Recombinant lactobacillus for fermentation of xylose to lactic acid and lactate. United States: N. p., 1998. Web.
Picataggio, Stephen K, Zhang, Min, Franden, Mary Ann, Mc Millan, James D, & Finkelstein, Mark. Recombinant lactobacillus for fermentation of xylose to lactic acid and lactate. United States.
Picataggio, Stephen K, Zhang, Min, Franden, Mary Ann, Mc Millan, James D, and Finkelstein, Mark. Thu . "Recombinant lactobacillus for fermentation of xylose to lactic acid and lactate". United States. https://www.osti.gov/servlets/purl/871796.
@article{osti_871796,
title = {Recombinant lactobacillus for fermentation of xylose to lactic acid and lactate},
author = {Picataggio, Stephen K and Zhang, Min and Franden, Mary Ann and Mc Millan, James D and Finkelstein, Mark},
abstractNote = {A recombinant Lactobacillus MONT4 is provided which has been genetically engineered with xylose isomerase and xylulokinase genes from Lactobacillus pentosus to impart to the Lactobacillus MONT4 the ability to ferment lignocellulosic biomass containing xylose to lactic acid.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1998},
month = {1}
}

Works referenced in this record:

Organization and characterization of three genes involved in d-xylose catabolism in Lactobacillus pentosus
journal, November 1991


Ethanol tolerance and carbohydrate metabolism in lactobacilli
journal, July 1992


Performance of microorganisms in spent sulfite liquor and enzymatic hydrolysate of steam-pretreatedSalix: Scientific note
journal, March 1992


Rapid Mini-Prep Isolation of High-Quality Plasmid DNA from Lactococcus and Lactobacillus spp. †
journal, January 1993


Carbohydrate metabolism in lactic acid bacteria
journal, January 1983


Molecular cloning in Lactobacillus helveticus by plasmid pSA3::pVA797 co-integrate formation and conjugal transfer
journal, June 1991


Promotor analysis and transcriptional regulation of Lactobacillus pentosus genes involved in xylose catabolism
journal, January 1994


Identification and sequence analysis of the Bacillus subtilis W23 xylR gene and xyl operator
journal, July 1989


Structural and functional analysis of two cryptic plasmids from Lactobacillus pentosus MD353 and Lactobacillus plantarum ATCC 8014
journal, August 1992


Complementation of the inability of Lactobacillus strains to utilize D-xylose with D-xylose catabolism-encoding genes of Lactobacillus pentosus.
journal, January 1991