Biomarkers of cell senescence
Abstract
The present invention provides a biomarker system for the in vivo and in vitro assessment of cell senescence. In the method of the present invention, .beta.-galactosidase activity is utilized as a means by which cell senescence may be assessed either in vitro cell cultures or in vivo.
- Inventors:
-
- (Simli U.P., IN)
- (Berkeley, CA)
- (Newton, MA)
- Issue Date:
- Research Org.:
- Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA
- OSTI Identifier:
- 871786
- Patent Number(s):
- 5795728
- Assignee:
- Regents of University of California (Oakland, CA) LBNL
- DOE Contract Number:
- AC03-76SF00098
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- biomarkers; cell; senescence; provides; biomarker; vivo; vitro; assessment; method; beta; -galactosidase; activity; utilized; means; assessed; cultures; cell senescence; cell culture; cell cultures; vitro assessment; vitro cell; -galactosidase activity; /435/436/
Citation Formats
Dimri, Goberdhan P., Campisi, Judith, and Peacocke, Monica. Biomarkers of cell senescence. United States: N. p., 1998.
Web.
Dimri, Goberdhan P., Campisi, Judith, & Peacocke, Monica. Biomarkers of cell senescence. United States.
Dimri, Goberdhan P., Campisi, Judith, and Peacocke, Monica. Thu .
"Biomarkers of cell senescence". United States. https://www.osti.gov/servlets/purl/871786.
@article{osti_871786,
title = {Biomarkers of cell senescence},
author = {Dimri, Goberdhan P. and Campisi, Judith and Peacocke, Monica},
abstractNote = {The present invention provides a biomarker system for the in vivo and in vitro assessment of cell senescence. In the method of the present invention, .beta.-galactosidase activity is utilized as a means by which cell senescence may be assessed either in vitro cell cultures or in vivo.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1998},
month = {1}
}
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