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Title: Computer-aided visualization and analysis system for sequence evaluation

Abstract

A computer system for analyzing nucleic acid sequences is provided. The computer system is used to perform multiple methods for determining unknown bases by analyzing the fluorescence intensities of hybridized nucleic acid probes. The results of individual experiments are improved by processing nucleic acid sequences together. Comparative analysis of multiple experiments is also provided by displaying reference sequences in one area and sample sequences in another area on a display device.

Inventors:
 [1]
  1. (3199 Waverly St., Palo Alto, CA 94306)
Issue Date:
Research Org.:
Affymetrix, Inc. (Santa Clara, CA)
OSTI Identifier:
871785
Patent Number(s):
5795716
Application Number:
08/327,525
Assignee:
Chee, Mark S. (3199 Waverly St., Palo Alto, CA 94306) OAK
DOE Contract Number:  
FG03-92ER81275
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
computer-aided; visualization; analysis; sequence; evaluation; computer; analyzing; nucleic; acid; sequences; provided; perform; multiple; methods; determining; bases; fluorescence; intensities; hybridized; probes; results; individual; experiments; improved; processing; comparative; displaying; reference; sample; display; device; comparative analysis; reference sequence; acid probes; acid sequence; nucleic acid; acid sequences; acid probe; display device; sequence evaluation; sample sequences; analyzing nucleic; processing nucleic; multiple experiments; multiple methods; computer-aided visualization; reference sequences; perform multiple; fluorescence intensities; form multiple; displaying reference; individual experiments; hybridized nucleic; /435/382/999/

Citation Formats

Chee, Mark S. Computer-aided visualization and analysis system for sequence evaluation. United States: N. p., 1998. Web.
Chee, Mark S. Computer-aided visualization and analysis system for sequence evaluation. United States.
Chee, Mark S. Tue . "Computer-aided visualization and analysis system for sequence evaluation". United States. https://www.osti.gov/servlets/purl/871785.
@article{osti_871785,
title = {Computer-aided visualization and analysis system for sequence evaluation},
author = {Chee, Mark S.},
abstractNote = {A computer system for analyzing nucleic acid sequences is provided. The computer system is used to perform multiple methods for determining unknown bases by analyzing the fluorescence intensities of hybridized nucleic acid probes. The results of individual experiments are improved by processing nucleic acid sequences together. Comparative analysis of multiple experiments is also provided by displaying reference sequences in one area and sample sequences in another area on a display device.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1998},
month = {8}
}

Patent:

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