Device of dispensing micro doses of aqueous solutions of substances onto a carrier and device for carrying out said method

Title: Device of dispensing micro doses of aqueous solutions of substances onto a carrier and device for carrying out said method

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Abstract

A device for dispensing microdoses of aqueous solutions are provided, whereby the substance is transferred by the free surface end of a rodlike transferring element; the temperature of the transferring element is maintained at essentially the dew point of the ambient air during the transfer. The device may comprise a plate-like base to which are affixed a plurality of rods; the unfixed butt ends of the rods are coplanar. The device further comprises a means for maintaining the temperature of the unfixed butt ends of the rods essentially equal to the dew point of the ambient air during transfer of the aqueous substance.

Inventors:

Ershow, Gennady Moiseevich ^[1]; Kirillov, Evgenii Vladislavovich ^[2]; Mirzabekov, Andrei Darievich ^[1]

Moscow, RU
gor. Dolgoprudnyi, RU

Issue Date:: 1998-01-01

Research Org.:: Argonne National Laboratory (ANL), Argonne, IL

OSTI Identifier:: 871568

Patent Number(s):: 5756050

Assignee:: University of Chicago (Chicago, IL)

Patent Classifications (CPCs):: B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01J - CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY

Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10T - TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION

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B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01J - CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY
B01J2219/00783 - Laminate assemblies, i.e. the reactor comprising a stack of plates

Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10T - TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
Y10T436/25625 - Dilution

B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01J - CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY
B01J2219/00873 - Heat exchange
B01J2219/00891 - Feeding or evacuation
B01J2219/0072 - Organic compounds

G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
G01N1/10 - in the liquid or fluent state {

B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01J - CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY
B01J2219/00605 - the compounds being directly bound or immobilised to solid supports

Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10T - TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
Y10T436/25 - including sample preparation

B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
B01L3/0244 - {using pins}

B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01J - CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY
B01J2219/00659 - Two-dimensional arrays
B01J2219/00961 - Temperature

Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10T - TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
Y10T436/12 - Condition responsive control

B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01J - CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY
B01J2219/00527 - Sheets
B01J2219/00585 - Parallel processes
B01J19/0046 - {Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides
B01J19/0093 - {Microreactors, e.g. miniaturised or microfabricated reactors
B01J2219/00387 - Applications using probes
B01J2219/00596 - Solid-phase processes

G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
G01N2035/1037 - {Using surface tension, e.g. pins or wires}

B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01J - CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY
B01J2219/00822 - Metal

Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10T - TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
Y10T436/115831 - Condition or time responsive
Y10T436/143333 - Saccharide [e.g., DNA, etc.]

B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01J - CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY
B01J2219/00828 - Silicon wafers or plates
B01J4/02 - for feeding measured {, i.e. prescribed} quantities of reagents

C - CHEMISTRY C40 - COMBINATORIAL TECHNOLOGY C40B - COMBINATORIAL CHEMISTRY
C40B60/14 - for creating libraries

B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01J - CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY
B01J2219/00995 - Mathematical modeling

Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10T - TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
Y10T436/119163 - with aspirator of claimed structure
Y10T436/2575 - Volumetric liquid transfer

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Resource Type:: Patent

Country of Publication:: United States

Language:: English

Subject:: device; dispensing; micro; doses; aqueous; solutions; substances; carrier; carrying; method; microdoses; provided; whereby; substance; transferred; free; surface; rodlike; transferring; element; temperature; maintained; essentially; dew; ambient; air; transfer; comprise; plate-like; base; affixed; plurality; rods; unfixed; butt; coplanar; comprises; means; maintaining; equal; essentially equal; ambient air; aqueous solution; aqueous solutions; free surface; /422/435/436/

Citation Formats


                    Ershow, Gennady Moiseevich, Kirillov, Evgenii Vladislavovich, and Mirzabekov, Andrei Darievich. Device of dispensing micro doses of aqueous solutions of substances onto a carrier and device for carrying out said method.  United States: N. p., 1998. 
        Web.

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                    Ershow, Gennady Moiseevich, Kirillov, Evgenii Vladislavovich, & Mirzabekov, Andrei Darievich. Device of dispensing micro doses of aqueous solutions of substances onto a carrier and device for carrying out said method.  United States.

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                    Ershow, Gennady Moiseevich, Kirillov, Evgenii Vladislavovich, and Mirzabekov, Andrei Darievich. Thu .  
        "Device of dispensing micro doses of aqueous solutions of substances onto a carrier and device for carrying out said method".  United States.  https://www.osti.gov/servlets/purl/871568.

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@article{osti_871568,

  title        = {Device of dispensing micro doses of aqueous solutions of substances onto a carrier and device for carrying out said method},

  author       = {Ershow, Gennady Moiseevich and Kirillov, Evgenii Vladislavovich and Mirzabekov, Andrei Darievich},

  abstractNote = {A device for dispensing microdoses of aqueous solutions are provided, whereby the substance is transferred by the free surface end of a rodlike transferring element; the temperature of the transferring element is maintained at essentially the dew point of the ambient air during the transfer. The device may comprise a plate-like base to which are affixed a plurality of rods; the unfixed butt ends of the rods are coplanar. The device further comprises a means for maintaining the temperature of the unfixed butt ends of the rods essentially equal to the dew point of the ambient air during transfer of the aqueous substance.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {1998},

  month        = {1}

}

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