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Title: Ultrasonic characterization of single drops of liquids

Abstract

Ultrasonic characterization of single drops of liquids. The present invention includes the use of two closely spaced transducers, or one transducer and a closely spaced reflector plate, to form an interferometer suitable for ultrasonic characterization of droplet-size and smaller samples without the need for a container. The droplet is held between the interferometer elements, whose distance apart may be adjusted, by surface tension. The surfaces of the interferometer elements may be readily cleansed by a stream of solvent followed by purified air when it is desired to change samples. A single drop of liquid is sufficient for high-quality measurement. Examples of samples which may be investigated using the apparatus and method of the present invention include biological specimens (tear drops; blood and other body fluid samples; samples from tumors, tissues, and organs; secretions from tissues and organs; snake and bee venom, etc.) for diagnostic evaluation, samples in forensic investigations, and detection of drugs in small quantities.

Inventors:
 [1]
  1. (Los Alamos, NM)
Issue Date:
Research Org.:
Los Alamos National Laboratory (LANL), Los Alamos, NM
OSTI Identifier:
871473
Patent Number(s):
5739432
Assignee:
Regents of University of California (Los Alamos, NM) LANL
DOE Contract Number:  
W-7405-ENG-36
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
ultrasonic; characterization; single; drops; liquids; closely; spaced; transducers; transducer; reflector; plate; form; interferometer; suitable; droplet-size; samples; container; droplet; held; elements; distance; apart; adjusted; surface; tension; surfaces; readily; cleansed; stream; solvent; followed; purified; air; desired; change; drop; liquid; sufficient; high-quality; measurement; examples; investigated; apparatus; method; biological; specimens; tear; blood; fluid; tumors; tissues; organs; secretions; snake; venom; etc; diagnostic; evaluation; forensic; investigations; detection; drugs; quantities; biological specimens; fluid sample; closely spaced; surface tension; fluid samples; solvent followed; ultrasonic characterization; distance apart; single drops; quality measurement; single drop; /73/

Citation Formats

Sinha, Dipen N. Ultrasonic characterization of single drops of liquids. United States: N. p., 1998. Web.
Sinha, Dipen N. Ultrasonic characterization of single drops of liquids. United States.
Sinha, Dipen N. Thu . "Ultrasonic characterization of single drops of liquids". United States. https://www.osti.gov/servlets/purl/871473.
@article{osti_871473,
title = {Ultrasonic characterization of single drops of liquids},
author = {Sinha, Dipen N.},
abstractNote = {Ultrasonic characterization of single drops of liquids. The present invention includes the use of two closely spaced transducers, or one transducer and a closely spaced reflector plate, to form an interferometer suitable for ultrasonic characterization of droplet-size and smaller samples without the need for a container. The droplet is held between the interferometer elements, whose distance apart may be adjusted, by surface tension. The surfaces of the interferometer elements may be readily cleansed by a stream of solvent followed by purified air when it is desired to change samples. A single drop of liquid is sufficient for high-quality measurement. Examples of samples which may be investigated using the apparatus and method of the present invention include biological specimens (tear drops; blood and other body fluid samples; samples from tumors, tissues, and organs; secretions from tissues and organs; snake and bee venom, etc.) for diagnostic evaluation, samples in forensic investigations, and detection of drugs in small quantities.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1998},
month = {1}
}

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