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Title: Biotin compounds for targetting tumors and sites of infection

Abstract

Novel biotin amide analogs that are useful for targeting therapeutic and imaging agents to sites of infection and tumors in vivo are disclosed.

Inventors:
 [1];  [1];  [2];  [3]
+ Show Inventor Affiliations
  1. Boston, MA
  2. De Catur, GA
  3. North Scituate, MA
Issue Date:
Research Org.:
Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States)
OSTI Identifier:
871360
Patent Number(s):
5716594
Assignee:
JMDE Trust (Newton, MA)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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DOE Contract Number:  
FG02-86ER60460
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
biotin; compounds; targetting; tumors; sites; infection; novel; amide; analogs; useful; targeting; therapeutic; imaging; agents; vivo; disclosed; imaging agents; imaging agent; /424/514/999/

Citation Formats

Elmaleh, David R, Fischman, Alan J, Shoup, Timothy M, and Babich, John W. Biotin compounds for targetting tumors and sites of infection. United States: N. p., 1998. Web.
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Elmaleh, David R, Fischman, Alan J, Shoup, Timothy M, & Babich, John W. Biotin compounds for targetting tumors and sites of infection. United States.
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Elmaleh, David R, Fischman, Alan J, Shoup, Timothy M, and Babich, John W. Thu . "Biotin compounds for targetting tumors and sites of infection". United States. https://www.osti.gov/servlets/purl/871360.
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@article{osti_871360,
title = {Biotin compounds for targetting tumors and sites of infection},
author = {Elmaleh, David R and Fischman, Alan J and Shoup, Timothy M and Babich, John W},
abstractNote = {Novel biotin amide analogs that are useful for targeting therapeutic and imaging agents to sites of infection and tumors in vivo are disclosed.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1998},
month = {1}
}
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Works referenced in this record:

Avidin binding of radiolabeled biotin derivatives.
journal, January 1988

An approach to the targeted attachment of peptides and proteins to solid supports.
journal, October 1976

99mTc Labeled Biotin Conjugate in a Tumor“Pretargeting” Approach with Monoclonal Antibodies
journal, November 1992

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