skip to main content
DOE Patents title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Nucleotide sequences encoding a thermostable alkaline protease

Abstract

Nucleotide sequences, derived from a thermophilic actinomycete microorganism, which encode a thermostable alkaline protease are disclosed. Also disclosed are variants of the nucleotide sequences which encode a polypeptide having thermostable alkaline proteolytic activity. Recombinant thermostable alkaline protease or recombinant polypeptide may be obtained by culturing in a medium a host cell genetically engineered to contain and express a nucleotide sequence according to the present invention, and recovering the recombinant thermostable alkaline protease or recombinant polypeptide from the culture medium.

Inventors:
 [1];  [2]
  1. Ithaca, NY
  2. Bethesda, MD
Issue Date:
Research Org.:
Cornell Univ., Ithaca, NY (United States)
OSTI Identifier:
871308
Patent Number(s):
5705379
Assignee:
Cornell Research Foundation, Inc. (Ithaca, NY)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
DOE Contract Number:  
FG02-84ER13233
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
nucleotide; sequences; encoding; thermostable; alkaline; protease; derived; thermophilic; actinomycete; microorganism; encode; disclosed; variants; polypeptide; proteolytic; activity; recombinant; obtained; culturing; medium; host; cell; genetically; engineered; contain; express; sequence; according; recovering; culture; sequences encoding; thermostable alkaline; culture medium; nucleotide sequences; nucleotide sequence; host cell; recombinant polypeptide; genetically engineered; alkaline protease; /435/999/

Citation Formats

Wilson, David B, and Lao, Guifang. Nucleotide sequences encoding a thermostable alkaline protease. United States: N. p., 1998. Web.
Wilson, David B, & Lao, Guifang. Nucleotide sequences encoding a thermostable alkaline protease. United States.
Wilson, David B, and Lao, Guifang. Thu . "Nucleotide sequences encoding a thermostable alkaline protease". United States. https://www.osti.gov/servlets/purl/871308.
@article{osti_871308,
title = {Nucleotide sequences encoding a thermostable alkaline protease},
author = {Wilson, David B and Lao, Guifang},
abstractNote = {Nucleotide sequences, derived from a thermophilic actinomycete microorganism, which encode a thermostable alkaline protease are disclosed. Also disclosed are variants of the nucleotide sequences which encode a polypeptide having thermostable alkaline proteolytic activity. Recombinant thermostable alkaline protease or recombinant polypeptide may be obtained by culturing in a medium a host cell genetically engineered to contain and express a nucleotide sequence according to the present invention, and recovering the recombinant thermostable alkaline protease or recombinant polypeptide from the culture medium.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1998},
month = {1}
}

Patent:

Save / Share: