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Title: Loading and conjugating cavity biostructures

Abstract

Methods for the preparation and use of a biological delivery system are disclosed. The method of preparation includes the loading of a non-biological material into a biostructure having a load-bearing structure. The method also includes the removal of some of the biostructure's contents and the loading of a non-biological material into the biostructure. The biostructure is biologically compatible with the host, and preferably is derived from the host, the host's species or a related species. The loaded biostructure is used directly, or it can be targeted to specific cells, tissues and/or organs within a host. The targeted biostructure can be used to deliver the non-biological material to a specified tissue, organ or cell within a host for diagnostic, therapeutic or other purposes.

Inventors:
 [1]
  1. 44 Bradley Dr., Shoreham, NY 11786
Issue Date:
Research Org.:
Associated Universities, Inc., Upton, NY (United States)
OSTI Identifier:
871248
Patent Number(s):
5690903
Application Number:
08/453,686
Assignee:
Hainfeld, James F. (44 Bradley Dr., Shoreham, NY 11786)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
DOE Contract Number:  
AC02-76CH00016
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
loading; conjugating; cavity; biostructures; methods; preparation; biological; delivery; disclosed; method; non-biological; material; biostructure; load-bearing; structure; removal; contents; biologically; compatible; host; preferably; derived; species; related; loaded; directly; targeted; specific; cells; tissues; organs; deliver; specified; tissue; organ; cell; diagnostic; therapeutic; purposes; non-biological material; specific cells; biological material; cavity biostructures; bearing structure; biological delivery; conjugating cavity; load-bearing structure; /424/

Citation Formats

Hainfeld, James F. Loading and conjugating cavity biostructures. United States: N. p., 1997. Web.
Hainfeld, James F. Loading and conjugating cavity biostructures. United States.
Hainfeld, James F. Tue . "Loading and conjugating cavity biostructures". United States. https://www.osti.gov/servlets/purl/871248.
@article{osti_871248,
title = {Loading and conjugating cavity biostructures},
author = {Hainfeld, James F},
abstractNote = {Methods for the preparation and use of a biological delivery system are disclosed. The method of preparation includes the loading of a non-biological material into a biostructure having a load-bearing structure. The method also includes the removal of some of the biostructure's contents and the loading of a non-biological material into the biostructure. The biostructure is biologically compatible with the host, and preferably is derived from the host, the host's species or a related species. The loaded biostructure is used directly, or it can be targeted to specific cells, tissues and/or organs within a host. The targeted biostructure can be used to deliver the non-biological material to a specified tissue, organ or cell within a host for diagnostic, therapeutic or other purposes.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Nov 25 00:00:00 EST 1997},
month = {Tue Nov 25 00:00:00 EST 1997}
}