DNA complexes with dyes designed for energy transfer as fluorescent markers
Abstract
Heteromultimeric fluorophores are provided for binding to DNA, which allow for the detection of DNA in electrical separations and preparation of probes having high-fluorescent efficiencies and large Stokes shifts. In addition, by appropriate choice of fluorescent molecules, one can use a single narrow wavelength band excitation light source, while obtaining fluorescent emissions having sufficient separation to be readily discriminated.
- Inventors:
-
- Orinda, CA
- Albany, CA
- Issue Date:
- Research Org.:
- Univ. of California (United States)
- OSTI Identifier:
- 871043
- Patent Number(s):
- 5646264
- Assignee:
- Regents of University of California (Oakland, CA)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07D - HETEROCYCLIC COMPOUNDS
C - CHEMISTRY C09 - DYES C09B - ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES {, e.g. PIGMENTS},
- DOE Contract Number:
- FG03-91ER61125
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- dna; complexes; dyes; designed; energy; transfer; fluorescent; markers; heteromultimeric; fluorophores; provided; binding; allow; detection; electrical; separations; preparation; probes; high-fluorescent; efficiencies; stokes; shifts; addition; appropriate; choice; molecules; single; narrow; wavelength; band; excitation; light; source; obtaining; emissions; sufficient; separation; readily; discriminated; stokes shifts; dyes designed; fluorescent molecules; single narrow; energy transfer; light source; excitation light; fluorescent emissions; wavelength band; narrow wavelength; readily discriminated; obtaining fluorescent; sufficient separation; electrical separations; dna complexes; high-fluorescent efficiencies; heteromultimeric fluorophores; fluorescent markers; band excitation; appropriate choice; fluorescent emission; stokes shift; /999/
Citation Formats
Glazer, Alexander N, and Benson, Scott C. DNA complexes with dyes designed for energy transfer as fluorescent markers. United States: N. p., 1997.
Web.
Glazer, Alexander N, & Benson, Scott C. DNA complexes with dyes designed for energy transfer as fluorescent markers. United States.
Glazer, Alexander N, and Benson, Scott C. Wed .
"DNA complexes with dyes designed for energy transfer as fluorescent markers". United States. https://www.osti.gov/servlets/purl/871043.
@article{osti_871043,
title = {DNA complexes with dyes designed for energy transfer as fluorescent markers},
author = {Glazer, Alexander N and Benson, Scott C},
abstractNote = {Heteromultimeric fluorophores are provided for binding to DNA, which allow for the detection of DNA in electrical separations and preparation of probes having high-fluorescent efficiencies and large Stokes shifts. In addition, by appropriate choice of fluorescent molecules, one can use a single narrow wavelength band excitation light source, while obtaining fluorescent emissions having sufficient separation to be readily discriminated.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Wed Jan 01 00:00:00 EST 1997},
month = {Wed Jan 01 00:00:00 EST 1997}
}
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