Miniaturized flow injection analysis system
Abstract
A chemical analysis technique known as flow injection analysis, wherein small quantities of chemical reagents and sample are intermixed and reacted within a capillary flow system and the reaction products are detected optically, electrochemically, or by other means. A highly miniaturized version of a flow injection analysis system has been fabricated utilizing microfabrication techniques common to the microelectronics industry. The microflow system uses flow capillaries formed by etching microchannels in a silicon or glass wafer followed by bonding to another wafer, commercially available microvalves bonded directly to the microflow channels, and an optical absorption detector cell formed near the capillary outlet, with light being both delivered and collected with fiber optics. The microflow system is designed mainly for analysis of liquids and currently measures 38.times.25.times.3 mm, but can be designed for gas analysis and be substantially smaller in construction.
- Inventors:
-
- Livermore, CA
- Issue Date:
- Research Org.:
- Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
- OSTI Identifier:
- 871029
- Patent Number(s):
- 5644395
- Assignee:
- Regents of University of California (Oakland, CA)
- Patent Classifications (CPCs):
-
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01J - CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- W-7405-ENG-48
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- miniaturized; flow; injection; analysis; chemical; technique; quantities; reagents; sample; intermixed; reacted; capillary; reaction; products; detected; optically; electrochemically; means; highly; version; fabricated; utilizing; microfabrication; techniques; common; microelectronics; industry; microflow; capillaries; formed; etching; microchannels; silicon; glass; wafer; followed; bonding; commercially; available; microvalves; bonded; directly; channels; optical; absorption; detector; cell; near; outlet; light; delivered; collected; fiber; optics; designed; mainly; liquids; currently; measures; 38; times; 25; gas; substantially; construction; gas analysis; flow injection; optical absorption; chemical analysis; fiber optics; flow channels; flow channel; fiber optic; reaction product; reaction products; commercially available; fabrication techniques; absorption detector; chemical reagent; detector cell; injection analysis; analysis technique; cell formed; chemical reagents; capillary flow; /356/
Citation Formats
Folta, James A. Miniaturized flow injection analysis system. United States: N. p., 1997.
Web.
Folta, James A. Miniaturized flow injection analysis system. United States.
Folta, James A. Wed .
"Miniaturized flow injection analysis system". United States. https://www.osti.gov/servlets/purl/871029.
@article{osti_871029,
title = {Miniaturized flow injection analysis system},
author = {Folta, James A},
abstractNote = {A chemical analysis technique known as flow injection analysis, wherein small quantities of chemical reagents and sample are intermixed and reacted within a capillary flow system and the reaction products are detected optically, electrochemically, or by other means. A highly miniaturized version of a flow injection analysis system has been fabricated utilizing microfabrication techniques common to the microelectronics industry. The microflow system uses flow capillaries formed by etching microchannels in a silicon or glass wafer followed by bonding to another wafer, commercially available microvalves bonded directly to the microflow channels, and an optical absorption detector cell formed near the capillary outlet, with light being both delivered and collected with fiber optics. The microflow system is designed mainly for analysis of liquids and currently measures 38.times.25.times.3 mm, but can be designed for gas analysis and be substantially smaller in construction.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1997},
month = {1}
}