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Title: Method and apparatus for detection of fluorescently labeled materials

Fluorescently marked targets bind to a substrate 230 synthesized with polymer sequences at known locations. The targets are detected by exposing selected regions of the substrate 230 to light from a light source 100 and detecting the photons from the light fluoresced therefrom, and repeating the steps of exposure and detection until the substrate 230 is completely examined. The resulting data can be used to determine binding affinity of the targets to specific polymer sequences.
Inventors:
 [1];  [2]
  1. (Mt. View, CA)
  2. (Los Altos, CA)
Issue Date:
OSTI Identifier:
870962
Assignee:
Affymetrix, Inc. (Santa Clara, CA) OAK
Patent Number(s):
US 5631734
Contract Number:
FG03-92ER81275
Research Org:
Affymax Research Institute
Country of Publication:
United States
Language:
English
Subject:
method; apparatus; detection; fluorescently; labeled; materials; marked; targets; bind; substrate; 230; synthesized; polymer; sequences; locations; detected; exposing; selected; regions; light; source; 100; detecting; photons; fluoresced; therefrom; repeating; steps; exposure; completely; examined; resulting; data; determine; binding; affinity; specific; light source; selected regions; resulting data; fluorescently labeled; selected region; specific polymer; /356/250/