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Title: Laser apparatus and method for microscopic and spectroscopic analysis and processing of biological cells

Abstract

An apparatus and method for microscopic and spectroscopic analysis and processing of biological cells. The apparatus comprises a laser having an analysis region within the laser cavity for containing one or more biological cells to be analyzed. The presence of a cell within the analysis region in superposition with an activated portion of a gain medium of the laser acts to encode information about the cell upon the laser beam, the cell information being recoverable by an analysis means that preferably includes an array photodetector such as a CCD camera and a spectrometer. The apparatus and method may be used to analyze biomedical cells including blood cells and the like, and may include processing means for manipulating, sorting, or eradicating cells after analysis thereof.

Inventors:
 [1];  [2]
  1. 12508 Loyola, NE., Albuquerque, NM 87112
  2. 7509 Spring Lake Dr., Apt. B1, Bethesda, MD 20817
Issue Date:
Research Org.:
SANDIA CORP
OSTI Identifier:
870852
Patent Number(s):
5608519
Assignee:
Gourley, Paul L. (12508 Loyola, NE., Albuquerque, NM 87112);Gourley, Mark F. (7509 Spring Lake Dr., Apt. B1, Bethesda, MD 20817)
DOE Contract Number:  
AC04-94AL85000
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
laser; apparatus; method; microscopic; spectroscopic; analysis; processing; biological; cells; comprises; region; cavity; containing; analyzed; presence; cell; superposition; activated; portion; medium; encode; information; beam; recoverable; means; preferably; array; photodetector; ccd; camera; spectrometer; analyze; biomedical; including; blood; manipulating; sorting; eradicating; analysis region; ccd camera; spectroscopic analysis; laser cavity; blood cells; apparatus comprises; laser beam; biological cells; laser apparatus; processing means; blood cell; apparatus comprise; activated portion; biological cell; /356/250/

Citation Formats

Gourley, Paul L, and Gourley, Mark F. Laser apparatus and method for microscopic and spectroscopic analysis and processing of biological cells. United States: N. p., 1997. Web.
Gourley, Paul L, & Gourley, Mark F. Laser apparatus and method for microscopic and spectroscopic analysis and processing of biological cells. United States.
Gourley, Paul L, and Gourley, Mark F. Wed . "Laser apparatus and method for microscopic and spectroscopic analysis and processing of biological cells". United States. https://www.osti.gov/servlets/purl/870852.
@article{osti_870852,
title = {Laser apparatus and method for microscopic and spectroscopic analysis and processing of biological cells},
author = {Gourley, Paul L and Gourley, Mark F},
abstractNote = {An apparatus and method for microscopic and spectroscopic analysis and processing of biological cells. The apparatus comprises a laser having an analysis region within the laser cavity for containing one or more biological cells to be analyzed. The presence of a cell within the analysis region in superposition with an activated portion of a gain medium of the laser acts to encode information about the cell upon the laser beam, the cell information being recoverable by an analysis means that preferably includes an array photodetector such as a CCD camera and a spectrometer. The apparatus and method may be used to analyze biomedical cells including blood cells and the like, and may include processing means for manipulating, sorting, or eradicating cells after analysis thereof.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1997},
month = {1}
}

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