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Title: Laser apparatus and method for microscopic and spectroscopic analysis and processing of biological cells

An apparatus and method for microscopic and spectroscopic analysis and processing of biological cells. The apparatus comprises a laser having an analysis region within the laser cavity for containing one or more biological cells to be analyzed. The presence of a cell within the analysis region in superposition with an activated portion of a gain medium of the laser acts to encode information about the cell upon the laser beam, the cell information being recoverable by an analysis means that preferably includes an array photodetector such as a CCD camera and a spectrometer. The apparatus and method may be used to analyze biomedical cells including blood cells and the like, and may include processing means for manipulating, sorting, or eradicating cells after analysis thereof.
Inventors:
 [1];  [2]
  1. (12508 Loyola, NE., Albuquerque, NM 87112)
  2. (7509 Spring Lake Dr., Apt. B1, Bethesda, MD 20817)
Issue Date:
OSTI Identifier:
870852
Assignee:
Gourley, Paul L. (12508 Loyola, NE., Albuquerque, NM 87112);Gourley, Mark F. (7509 Spring Lake Dr., Apt. B1, Bethesda, MD 20817) SNL
Patent Number(s):
US 5608519
Contract Number:
AC04-94AL85000
Research Org:
SANDIA CORP
Country of Publication:
United States
Language:
English
Subject:
laser; apparatus; method; microscopic; spectroscopic; analysis; processing; biological; cells; comprises; region; cavity; containing; analyzed; presence; cell; superposition; activated; portion; medium; encode; information; beam; recoverable; means; preferably; array; photodetector; ccd; camera; spectrometer; analyze; biomedical; including; blood; manipulating; sorting; eradicating; analysis region; ccd camera; spectroscopic analysis; laser cavity; blood cells; apparatus comprises; laser beam; biological cells; laser apparatus; processing means; blood cell; apparatus comprise; activated portion; biological cell; /356/250/

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