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Title: Sample introduction system for a flow cytometer

A sample introduction system for a flow cytometer allows easy change of sample containers such as test tubes and facilitates use in high pressure environments. The sample container includes a cap having a pressure supply chamber and a sample container attachment cavity. A sample container may be automatically positioned into the attachment cavity so as to sealably engage the end of the sample container as its outer surface. This positioning may be accomplished through some sample introduction mechanism. To facilitate cleaning, HPLC tubing and fittings may be used in a manner which facilitates removing of the entire tubing from both the nozzle container and other sample container cap to permit its replacement to avoid contamination. The sample container support may include horizontal stops which loosely limit the movement of the sample container and thus avoid further stresses upon it.
  1. (Seattle, WA)
Issue Date:
OSTI Identifier:
University of Washington (Seattle, WA) LLNL
Patent Number(s):
US 5602349
Contract Number:
Research Org:
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
Country of Publication:
United States
sample; introduction; flow; cytometer; allows; easy; change; containers; tubes; facilitates; pressure; environments; container; cap; supply; chamber; attachment; cavity; automatically; positioned; sealably; engage; outer; surface; positioning; accomplished; mechanism; facilitate; cleaning; hplc; tubing; fittings; manner; removing; entire; nozzle; permit; replacement; avoid; contamination; support; horizontal; stops; loosely; limit; movement; stresses; avoid contamination; pressure environment; pressure supply; sample container; outer surface; flow cytometer; sample introduction; nozzle container; sealably engage; sample containers; pressure environments; allows easy; easy change; cytometer allows; container support; container cap; /73/