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Title: System and method for forming synthetic protein crystals to determine the conformational structure by crystallography

Abstract

A method for forming synthetic crystals of proteins in a carrier fluid by use of the dipole moments of protein macromolecules that self-align in the Helmholtz layer adjacent to an electrode. The voltage gradients of such layers easily exceed 10.sup.6 V/m. The synthetic protein crystals are subjected to x-ray crystallography to determine the conformational structure of the protein involved.

Inventors:
 [1];  [2];  [3]
  1. Lafayette, CA
  2. Livermore, CA
  3. Dublin, CA
Issue Date:
Research Org.:
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
OSTI Identifier:
870801
Patent Number(s):
5597457
Assignee:
Regents of University of California (Oakland, CA)
DOE Contract Number:  
W-7405-ENG-48
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
method; forming; synthetic; protein; crystals; determine; conformational; structure; crystallography; proteins; carrier; fluid; dipole; moments; macromolecules; self-align; helmholtz; layer; adjacent; electrode; voltage; gradients; layers; easily; exceed; 10; subjected; x-ray; involved; carrier fluid; forming synthetic; voltage gradient; layer adjacent; dipole moment; protein crystal; dipole moments; /204/205/378/435/

Citation Formats

Craig, George D, Glass, Robert, and Rupp, Bernhard. System and method for forming synthetic protein crystals to determine the conformational structure by crystallography. United States: N. p., 1997. Web.
Craig, George D, Glass, Robert, & Rupp, Bernhard. System and method for forming synthetic protein crystals to determine the conformational structure by crystallography. United States.
Craig, George D, Glass, Robert, and Rupp, Bernhard. Wed . "System and method for forming synthetic protein crystals to determine the conformational structure by crystallography". United States. https://www.osti.gov/servlets/purl/870801.
@article{osti_870801,
title = {System and method for forming synthetic protein crystals to determine the conformational structure by crystallography},
author = {Craig, George D and Glass, Robert and Rupp, Bernhard},
abstractNote = {A method for forming synthetic crystals of proteins in a carrier fluid by use of the dipole moments of protein macromolecules that self-align in the Helmholtz layer adjacent to an electrode. The voltage gradients of such layers easily exceed 10.sup.6 V/m. The synthetic protein crystals are subjected to x-ray crystallography to determine the conformational structure of the protein involved.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1997},
month = {1}
}

Patent:

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