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Title: System and method for forming synthetic protein crystals to determine the conformational structure by crystallography

A method for forming synthetic crystals of proteins in a carrier fluid by use of the dipole moments of protein macromolecules that self-align in the Helmholtz layer adjacent to an electrode. The voltage gradients of such layers easily exceed 10.sup.6 V/m. The synthetic protein crystals are subjected to x-ray crystallography to determine the conformational structure of the protein involved.
Inventors:
 [1];  [2];  [3]
  1. (Lafayette, CA)
  2. (Livermore, CA)
  3. (Dublin, CA)
Issue Date:
OSTI Identifier:
870801
Assignee:
Regents of University of California (Oakland, CA) LLNL
Patent Number(s):
US 5597457
Contract Number:
W-7405-ENG-48
Research Org:
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
Country of Publication:
United States
Language:
English
Subject:
method; forming; synthetic; protein; crystals; determine; conformational; structure; crystallography; proteins; carrier; fluid; dipole; moments; macromolecules; self-align; helmholtz; layer; adjacent; electrode; voltage; gradients; layers; easily; exceed; 10; subjected; x-ray; involved; carrier fluid; forming synthetic; voltage gradient; layer adjacent; dipole moment; protein crystal; dipole moments; /204/205/378/435/

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