System and method for forming synthetic protein crystals to determine the conformational structure by crystallography
Abstract
A method for forming synthetic crystals of proteins in a carrier fluid by use of the dipole moments of protein macromolecules that self-align in the Helmholtz layer adjacent to an electrode. The voltage gradients of such layers easily exceed 10.sup.6 V/m. The synthetic protein crystals are subjected to x-ray crystallography to determine the conformational structure of the protein involved.
- Inventors:
-
- Lafayette, CA
- Livermore, CA
- Dublin, CA
- Issue Date:
- Research Org.:
- Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
- OSTI Identifier:
- 870801
- Patent Number(s):
- 5597457
- Assignee:
- Regents of University of California (Oakland, CA)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C10 - PETROLEUM, GAS OR COKE INDUSTRIES C10M - LUBRICATING COMPOSITIONS
C - CHEMISTRY C30 - CRYSTAL GROWTH C30B - SINGLE-CRYSTAL-GROWTH
- DOE Contract Number:
- W-7405-ENG-48
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- method; forming; synthetic; protein; crystals; determine; conformational; structure; crystallography; proteins; carrier; fluid; dipole; moments; macromolecules; self-align; helmholtz; layer; adjacent; electrode; voltage; gradients; layers; easily; exceed; 10; subjected; x-ray; involved; carrier fluid; forming synthetic; voltage gradient; layer adjacent; dipole moment; protein crystal; dipole moments; /204/205/378/435/
Citation Formats
Craig, George D, Glass, Robert, and Rupp, Bernhard. System and method for forming synthetic protein crystals to determine the conformational structure by crystallography. United States: N. p., 1997.
Web.
Craig, George D, Glass, Robert, & Rupp, Bernhard. System and method for forming synthetic protein crystals to determine the conformational structure by crystallography. United States.
Craig, George D, Glass, Robert, and Rupp, Bernhard. Wed .
"System and method for forming synthetic protein crystals to determine the conformational structure by crystallography". United States. https://www.osti.gov/servlets/purl/870801.
@article{osti_870801,
title = {System and method for forming synthetic protein crystals to determine the conformational structure by crystallography},
author = {Craig, George D and Glass, Robert and Rupp, Bernhard},
abstractNote = {A method for forming synthetic crystals of proteins in a carrier fluid by use of the dipole moments of protein macromolecules that self-align in the Helmholtz layer adjacent to an electrode. The voltage gradients of such layers easily exceed 10.sup.6 V/m. The synthetic protein crystals are subjected to x-ray crystallography to determine the conformational structure of the protein involved.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1997},
month = {1}
}
Save to My Library
You must Sign In or Create an Account in order to save documents to your library.
Works referenced in this record:
Epitaxial growth of protein crystals on lipid layers
journal, March 1994
- Edward, Aled M.; Darst, Seth A.; Hemming, Sally A.
- Nature Structural Biology, Vol. 1, Issue 3
Voltage-dependent ordering of water molecules at an electrode–electrolyte interface
journal, March 1994
- Toney, Michael F.; Howard, Jason N.; Richer, Jocelyn
- Nature, Vol. 368, Issue 6470
Meeting Briefs: Search for Better Crystals Explores Inner, Outer Space
journal, December 1995
- Normile, D.
- Science, Vol. 270, Issue 5244
Electric-Field-Enhanced Self-Assembly of .alpha.-helical polypeptides
journal, October 1995
- Worley, Christopher G.; Linton, Richard W.; Samulski, Edward T.
- Langmuir, Vol. 11, Issue 10
Electrically-Induced Memory Effect in Bacteriorhodopsin
journal, April 1995
- Okazaki, Choichiro; Takeda, Kazuo
- Japanese Journal of Applied Physics, Vol. 34, Issue Part 1, No. 4A