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Title: Detection and prevention of mycoplasma hominis infection

Abstract

The present invention is directed to a rapid and sensitive method for detecting Mycoplasma hominis using M. hominis-specific probes, oligonucleotides or antibodies. In particular a target sequence can be amplified by in vitro nucleic acid amplification techniques, detected by nucleic acid hybridization using the subject probes and oligonucleotides or detected by immunoassay using M. hominis-specific antibodies. M. hominis-specific nucleic acids which do not recognize or hybridize to genomic nucleic acid of other Mycoplasma species are also provided.

Inventors:
 [1];  [2];  [3]
  1. Scranton, PA
  2. Philadelphia, PA
  3. San Antonio, TX
Issue Date:
Research Org.:
United States Air Force
OSTI Identifier:
870792
Patent Number(s):
5595871
Application Number:
08/112,816
Assignee:
University of Scranton (Scranton, PA); Research Corporation Technologies, Inc. (Tucson, AZ)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
DOE Contract Number:  
F49620-85-C001; F49620-88-C0053
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
detection; prevention; mycoplasma; hominis; infection; directed; rapid; sensitive; method; detecting; hominis-specific; probes; oligonucleotides; antibodies; particular; target; sequence; amplified; vitro; nucleic; acid; amplification; techniques; detected; hybridization; subject; immunoassay; acids; recognize; hybridize; genomic; species; provided; acid hybridization; nucleic acid; nucleic acids; target sequence; specific nucleic; specific probe; acid amplification; sensitive method; mycoplasma hominis; /435/999/

Citation Formats

DelVecchio, Vito G, Gallia, Gary L, and McCleskey, Ferne K. Detection and prevention of mycoplasma hominis infection. United States: N. p., 1997. Web.
DelVecchio, Vito G, Gallia, Gary L, & McCleskey, Ferne K. Detection and prevention of mycoplasma hominis infection. United States.
DelVecchio, Vito G, Gallia, Gary L, and McCleskey, Ferne K. Wed . "Detection and prevention of mycoplasma hominis infection". United States. https://www.osti.gov/servlets/purl/870792.
@article{osti_870792,
title = {Detection and prevention of mycoplasma hominis infection},
author = {DelVecchio, Vito G and Gallia, Gary L and McCleskey, Ferne K},
abstractNote = {The present invention is directed to a rapid and sensitive method for detecting Mycoplasma hominis using M. hominis-specific probes, oligonucleotides or antibodies. In particular a target sequence can be amplified by in vitro nucleic acid amplification techniques, detected by nucleic acid hybridization using the subject probes and oligonucleotides or detected by immunoassay using M. hominis-specific antibodies. M. hominis-specific nucleic acids which do not recognize or hybridize to genomic nucleic acid of other Mycoplasma species are also provided.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1997},
month = {1}
}

Works referenced in this record:

Quantitative genetics of zinc hyperaccumulation in Thlaspi caerulescens
journal, January 1996


Antibodies of Predetermined Specificity in Biology and Medicine
book, January 1984


Papers accepted for publication in chromatographia
journal, August 1987


Development of a DNA probe for Ureaplasma urealyticum
journal, October 1992