Dimeric fluorescent energy transfer dyes comprising asymmetric cyanine azole-indolenine chromophores
Abstract
Novel fluorescent DNA-staining dyes are provided combining asymmetric cyanine azole-indolenine dyes, which provide for strong DNA affinity, large Stokes shifts and emission in the red region of the spectrum. The dyes find particular application in gel electrophoresis and for labels which may be bound to a variety of compositions in a variety of contexts.
- Inventors:
-
- Orinda, CA
- Albany, CA
- Issue Date:
- Research Org.:
- Univ. of California (United States)
- OSTI Identifier:
- 870642
- Patent Number(s):
- 5565554
- Assignee:
- Regents of University of California (Oakland, CA)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07D - HETEROCYCLIC COMPOUNDS
C - CHEMISTRY C09 - DYES C09B - ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES {, e.g. PIGMENTS},
- DOE Contract Number:
- FG03-91ER61125
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- dimeric; fluorescent; energy; transfer; dyes; comprising; asymmetric; cyanine; azole-indolenine; chromophores; novel; dna-staining; provided; combining; provide; strong; dna; affinity; stokes; shifts; emission; region; spectrum; particular; application; electrophoresis; labels; bound; variety; compositions; contexts; novel fluorescent; stokes shifts; particular application; energy transfer; transfer dyes; cyanine azole-indolenine; asymmetric cyanine; provided combining; strong dna; comprising asymmetric; combining asymmetric; fluorescent energy; stokes shift; azole-indolenine chromophores; azole-indolenine dyes; dyes comprising; dimeric fluorescent; dna affinity; /999/
Citation Formats
Glazer, Alexander N, and Benson, Scott C. Dimeric fluorescent energy transfer dyes comprising asymmetric cyanine azole-indolenine chromophores. United States: N. p., 1996.
Web.
Glazer, Alexander N, & Benson, Scott C. Dimeric fluorescent energy transfer dyes comprising asymmetric cyanine azole-indolenine chromophores. United States.
Glazer, Alexander N, and Benson, Scott C. Mon .
"Dimeric fluorescent energy transfer dyes comprising asymmetric cyanine azole-indolenine chromophores". United States. https://www.osti.gov/servlets/purl/870642.
@article{osti_870642,
title = {Dimeric fluorescent energy transfer dyes comprising asymmetric cyanine azole-indolenine chromophores},
author = {Glazer, Alexander N and Benson, Scott C},
abstractNote = {Novel fluorescent DNA-staining dyes are provided combining asymmetric cyanine azole-indolenine dyes, which provide for strong DNA affinity, large Stokes shifts and emission in the red region of the spectrum. The dyes find particular application in gel electrophoresis and for labels which may be bound to a variety of compositions in a variety of contexts.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1996},
month = {1}
}
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Works referenced in this record:
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- Chemistry of Heterocyclic Compounds: A Series Of Monographs
Cyanine dye labeling reagents for sulfhydryl groups
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Heterodimeric DNA-binding dyes designed for energy transfer: stability and applications of the DNA complexes
journal, January 1993
- Benson, Scott C.; Mathies, Richard A.; Glazer, Alexander N.
- Nucleic Acids Research, Vol. 21, Issue 24
Stable fluorescent complexes of double-stranded DNA with bis-intercalating asymmetric cyanine dyes: properties and applications
journal, January 1992
- Rye, Hays S.; Yue, Stephen; Wemmer, David E.
- Nucleic Acids Research, Vol. 20, Issue 11