Recombinant HT.sub.m4 gene, protein and assays

Lim, Bing; Adra, Chaker N; Lelias, Jean-Michel

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Title: Recombinant HT.sub.m4 gene, protein and assays

Abstract

The invention relates to a recombinant DNA molecule which encodes a HT.sub.m4 protein, a transformed host cell which has been stably transfected with a DNA molecule which encodes a HT.sub.m4 protein and a recombinant HT.sub.m4 protein. The invention also relates to a method for detecting the presence of a hereditary atopy.

Inventors:

Lim, Bing ^[1]; Adra, Chaker N ^[2]; Lelias, Jean-Michel ^[3]

Dorcester, MA
Boston, MA
Toulouse, FR

Issue Date:: Mon Jan 01 00:00:00 EST 1996

Research Org.:: Univ. of Chicago, IL (United States)

OSTI Identifier:: 870590

Patent Number(s):: 5552312

Assignee:: Beth Israel Hospital Boston (Boston, MA)

Patent Classifications (CPCs):: C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES

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C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
C07K14/70596 - {Molecules with a "CD"-designation not provided for elsewhere}

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DOE Contract Number:: FG02-86ER60408

Resource Type:: Patent

Country of Publication:: United States

Language:: English

Subject:: recombinant; m4; protein; assays; relates; dna; molecule; encodes; transformed; host; cell; stably; transfected; method; detecting; presence; hereditary; atopy; recombinant dna; m4 protein; host cell; dna molecule; stably transfected; transformed host; hereditary atopy; /435/999/

Citation Formats


                    Lim, Bing, Adra, Chaker N, and Lelias, Jean-Michel. Recombinant HT.sub.m4 gene, protein and assays.  United States: N. p., 1996. 
        Web.

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                    Lim, Bing, Adra, Chaker N, & Lelias, Jean-Michel. Recombinant HT.sub.m4 gene, protein and assays.  United States.

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                    Lim, Bing, Adra, Chaker N, and Lelias, Jean-Michel. Mon .  
        "Recombinant HT.sub.m4 gene, protein and assays".  United States.  https://www.osti.gov/servlets/purl/870590.

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@article{osti_870590,

  title        = {Recombinant HT.sub.m4 gene, protein and assays},

  author       = {Lim, Bing and Adra, Chaker N and Lelias, Jean-Michel},

  abstractNote = {The invention relates to a recombinant DNA molecule which encodes a HT.sub.m4 protein, a transformed host cell which has been stably transfected with a DNA molecule which encodes a HT.sub.m4 protein and a recombinant HT.sub.m4 protein. The invention also relates to a method for detecting the presence of a hereditary atopy.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {Mon Jan 01 00:00:00 EST 1996},

  month        = {Mon Jan 01 00:00:00 EST 1996}

}

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Works referenced in this record:

A major gene for allergy — fact or fancy?
journal, December 1992

Marsh, David G.; Meyers, Deborah A.
Nature Genetics, Vol. 2, Issue 4
https://doi.org/10.1038/ng1292-252

Fc Receptors
journal, April 1991

Ravetch, J. V.; Kinet, J. P.
Annual Review of Immunology, Vol. 9, Issue 1
https://doi.org/10.1146/annurev.iy.09.040191.002325

Isolation and characterization of cDNAs coding for the beta subunit of the high-affinity receptor for immunoglobulin E.
journal, September 1988

Kinet, J. P.; Blank, U.; Ra, C.
Proceedings of the National Academy of Sciences, Vol. 85, Issue 17
https://doi.org/10.1073/pnas.85.17.6483

Association between atopy and variants of the β subunit of the high–affinity immunoglobulin E receptor
journal, June 1994

Shirakawa, Taro; Li, Airong; Dubowitz, Michael
Nature Genetics, Vol. 7, Issue 2
https://doi.org/10.1038/ng0694-125

Atopy and Fc receptors: mutation is the message?
journal, June 1994

Ravetch, Jeffrey V.
Nature Genetics, Vol. 7, Issue 2
https://doi.org/10.1038/ng0694-117

LINKAGE BETWEEN IMMUNOGLOBULIN E RESPONSES UNDERLYING ASTHMA AND RHINITIS AND CHROMOSOME 11q
journal, June 1989

Cookson, WilliamO. C. M.; Faux, JenniferA.; Sharp, PamelaA.
The Lancet, Vol. 333, Issue 8650
https://doi.org/10.1016/S0140-6736(89)92687-1

The gene and cDNA for the human high affinity immunoglobulin E receptor beta chain and expression of the complete human receptor.
journal, June 1992

Küster, H.; Zhang, L.; Brini, A. T.
Journal of Biological Chemistry, Vol. 267, Issue 18
https://doi.org/10.1016/S0021-9258(18)42344-7

Complete structure of the mouse mast cell receptor for IgE (Fc ϵ RI) and surface expression of chimeric receptors (rat-mouse-human) on transfected cells
journal, September 1989

Ra, C.; Jouvin, M. H.; Kinet, J. P.
Journal of Biological Chemistry, Vol. 264, Issue 26
https://doi.org/10.1016/S0021-9258(19)84829-9

Determination of the sequence coding for the β subunit of the human high-affinity IgE receptor
journal, May 1992

Maekawa, Kazuhiko; Imagawa, Noriko; Tanaka, Yoshiaki
FEBS Letters, Vol. 302, Issue 2
https://doi.org/10.1016/0014-5793(92)80430-O

Allergy by mutation
journal, June 1994

Davies, Kevin
Nature, Vol. 369, Issue 6480
https://doi.org/10.1038/369506a0

Cloning of the cDNA for a hematopoietic cell-specific protein related to CD20 and the beta subunit of the high-affinity IgE receptor: evidence for a family of proteins with four membrane-spanning regions.
journal, October 1994

Adra, C. N.; Lelias, J. M.; Kobayashi, H.
Proceedings of the National Academy of Sciences, Vol. 91, Issue 21
https://doi.org/10.1073/pnas.91.21.10178

Maternal inheritance of atopic IgE responsiveness on chromosome 11 q
journal, August 1992

Cookson, W. O. C. M.; Young, R. P.; Sandford, A. J.
The Lancet, Vol. 340, Issue 8816
https://doi.org/10.1016/0140-6736(92)91468-N

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Similar Records

Title: Recombinant HT.sub.m4 gene, protein and assays

Abstract

Citation Formats

A major gene for allergy — fact or fancy? journal, December 1992

Fc Receptors journal, April 1991

Isolation and characterization of cDNAs coding for the beta subunit of the high-affinity receptor for immunoglobulin E. journal, September 1988

Association between atopy and variants of the β subunit of the high–affinity immunoglobulin E receptor journal, June 1994

Atopy and Fc receptors: mutation is the message? journal, June 1994

LINKAGE BETWEEN IMMUNOGLOBULIN E RESPONSES UNDERLYING ASTHMA AND RHINITIS AND CHROMOSOME 11q journal, June 1989

The gene and cDNA for the human high affinity immunoglobulin E receptor beta chain and expression of the complete human receptor. journal, June 1992

Complete structure of the mouse mast cell receptor for IgE (Fc ϵ RI) and surface expression of chimeric receptors (rat-mouse-human) on transfected cells journal, September 1989

Determination of the sequence coding for the β subunit of the human high-affinity IgE receptor journal, May 1992

Allergy by mutation journal, June 1994

Cloning of the cDNA for a hematopoietic cell-specific protein related to CD20 and the beta subunit of the high-affinity IgE receptor: evidence for a family of proteins with four membrane-spanning regions. journal, October 1994

Maternal inheritance of atopic IgE responsiveness on chromosome 11 q journal, August 1992

A major gene for allergy — fact or fancy?
journal, December 1992

Fc Receptors
journal, April 1991

Isolation and characterization of cDNAs coding for the beta subunit of the high-affinity receptor for immunoglobulin E.
journal, September 1988

Association between atopy and variants of the β subunit of the high–affinity immunoglobulin E receptor
journal, June 1994

Atopy and Fc receptors: mutation is the message?
journal, June 1994

LINKAGE BETWEEN IMMUNOGLOBULIN E RESPONSES UNDERLYING ASTHMA AND RHINITIS AND CHROMOSOME 11q
journal, June 1989

The gene and cDNA for the human high affinity immunoglobulin E receptor beta chain and expression of the complete human receptor.
journal, June 1992

Complete structure of the mouse mast cell receptor for IgE (Fc ϵ RI) and surface expression of chimeric receptors (rat-mouse-human) on transfected cells
journal, September 1989

Determination of the sequence coding for the β subunit of the human high-affinity IgE receptor
journal, May 1992

Allergy by mutation
journal, June 1994

Cloning of the cDNA for a hematopoietic cell-specific protein related to CD20 and the beta subunit of the high-affinity IgE receptor: evidence for a family of proteins with four membrane-spanning regions.
journal, October 1994

Maternal inheritance of atopic IgE responsiveness on chromosome 11 q
journal, August 1992