Ion-induced nuclear radiotherapy
Abstract
Ion-induced Nuclear Radiotherapy (INRT) is a technique for conducting radiosurgery and radiotherapy with a very high degree of control over the spatial extent of the irradiated volume and the delivered dose. Based upon the concept that low energy, ion induced atomic and nuclear reactions can be used to produce highly energetic reaction products at the site of a tumor, the INRT technique is implemented through the use of a conduit-needle or tube which conducts a low energy ion beam to a position above or within the intended treatment area. At the end of the conduit-needle or tube is a specially fabricated target which, only when struck by the ion beam, acts as a source of energetic radiation products. The inherent limitations in the energy, and therefore range, of the resulting reaction products limits the spatial extent of irradiation to a pre-defined volume about the point of reaction. Furthermore, since no damage is done to tissue outside this irradiated volume, the delivered dose may be made arbitrarily large. INRT may be used both as a point-source of radiation at the site of a small tumor, or as a topical bath of radiation to broad areas of diseased tissue.
- Inventors:
-
- Albuquerque, NM
- Issue Date:
- Research Org.:
- AT&T
- OSTI Identifier:
- 870567
- Patent Number(s):
- 5547454
- Assignee:
- Sandia Corporation (Albuquerque, NM)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61N - ELECTROTHERAPY
- DOE Contract Number:
- AC04-76DP00789
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- ion-induced; nuclear; radiotherapy; inrt; technique; conducting; radiosurgery; degree; control; spatial; extent; irradiated; volume; delivered; dose; based; concept; energy; induced; atomic; reactions; produce; highly; energetic; reaction; products; site; tumor; implemented; conduit-needle; tube; conducts; beam; position; intended; treatment; specially; fabricated; target; struck; source; radiation; inherent; limitations; range; resulting; limits; irradiation; pre-defined; furthermore; damage; tissue; outside; arbitrarily; point-source; topical; bath; broad; diseased; nuclear reactions; reaction product; reaction products; nuclear reaction; resulting reaction; produce highly; nuclear radiotherapy; diseased tissue; inherent limitations; ion-induced nuclear; /600/250/
Citation Formats
Horn, Kevin M, and Doyle, Barney L. Ion-induced nuclear radiotherapy. United States: N. p., 1996.
Web.
Horn, Kevin M, & Doyle, Barney L. Ion-induced nuclear radiotherapy. United States.
Horn, Kevin M, and Doyle, Barney L. Mon .
"Ion-induced nuclear radiotherapy". United States. https://www.osti.gov/servlets/purl/870567.
@article{osti_870567,
title = {Ion-induced nuclear radiotherapy},
author = {Horn, Kevin M and Doyle, Barney L},
abstractNote = {Ion-induced Nuclear Radiotherapy (INRT) is a technique for conducting radiosurgery and radiotherapy with a very high degree of control over the spatial extent of the irradiated volume and the delivered dose. Based upon the concept that low energy, ion induced atomic and nuclear reactions can be used to produce highly energetic reaction products at the site of a tumor, the INRT technique is implemented through the use of a conduit-needle or tube which conducts a low energy ion beam to a position above or within the intended treatment area. At the end of the conduit-needle or tube is a specially fabricated target which, only when struck by the ion beam, acts as a source of energetic radiation products. The inherent limitations in the energy, and therefore range, of the resulting reaction products limits the spatial extent of irradiation to a pre-defined volume about the point of reaction. Furthermore, since no damage is done to tissue outside this irradiated volume, the delivered dose may be made arbitrarily large. INRT may be used both as a point-source of radiation at the site of a small tumor, or as a topical bath of radiation to broad areas of diseased tissue.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1996},
month = {1}
}
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