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Title: Ion current detector for high pressure ion sources for monitoring separations

Abstract

The present invention relates generally to any application involving the monitoring of signal arising from ions produced by electrospray or other high pressure (>100 torr) ion sources. The present invention relates specifically to an apparatus and method for the detection of ions emitted from a capillary electrophoresis (CE) system, liquid chromatography, or other small-scale separation methods. And further, the invention provides a very simple diagnostic as to the quality of the separation and the operation of an electrospray source.

Inventors:
 [1];  [1];  [1]
  1. Richland, WA
Issue Date:
Research Org.:
Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
OSTI Identifier:
870554
Patent Number(s):
5545304
Assignee:
Battelle Memorial Institute (Richland, WA)
Patent Classifications (CPCs):
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
H - ELECTRICITY H01 - BASIC ELECTRIC ELEMENTS H01J - ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
DOE Contract Number:  
AC06-76RL01830
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
current; detector; pressure; sources; monitoring; separations; relates; application; involving; signal; arising; produced; electrospray; 100; torr; specifically; apparatus; method; detection; emitted; capillary; electrophoresis; liquid; chromatography; small-scale; separation; methods; provides; simple; diagnostic; quality; operation; source; liquid chromatograph; capillary electrophoresis; liquid chromatography; separation method; scale separation; current detector; /204/73/250/

Citation Formats

Smith, Richard D, Wahl, Jon H, and Hofstadler, Steven A. Ion current detector for high pressure ion sources for monitoring separations. United States: N. p., 1996. Web.
Smith, Richard D, Wahl, Jon H, & Hofstadler, Steven A. Ion current detector for high pressure ion sources for monitoring separations. United States.
Smith, Richard D, Wahl, Jon H, and Hofstadler, Steven A. Mon . "Ion current detector for high pressure ion sources for monitoring separations". United States. https://www.osti.gov/servlets/purl/870554.
@article{osti_870554,
title = {Ion current detector for high pressure ion sources for monitoring separations},
author = {Smith, Richard D and Wahl, Jon H and Hofstadler, Steven A},
abstractNote = {The present invention relates generally to any application involving the monitoring of signal arising from ions produced by electrospray or other high pressure (>100 torr) ion sources. The present invention relates specifically to an apparatus and method for the detection of ions emitted from a capillary electrophoresis (CE) system, liquid chromatography, or other small-scale separation methods. And further, the invention provides a very simple diagnostic as to the quality of the separation and the operation of an electrospray source.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Mon Jan 01 00:00:00 EST 1996},
month = {Mon Jan 01 00:00:00 EST 1996}
}