Ion current detector for high pressure ion sources for monitoring separations

Smith, Richard D; Wahl, Jon H; Hofstadler, Steven A

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Title: Ion current detector for high pressure ion sources for monitoring separations

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Abstract

The present invention relates generally to any application involving the monitoring of signal arising from ions produced by electrospray or other high pressure (>100 torr) ion sources. The present invention relates specifically to an apparatus and method for the detection of ions emitted from a capillary electrophoresis (CE) system, liquid chromatography, or other small-scale separation methods. And further, the invention provides a very simple diagnostic as to the quality of the separation and the operation of an electrospray source.

Inventors:

Smith, Richard D ^[1]; Wahl, Jon H ^[1]; Hofstadler, Steven A ^[1]

Richland, WA

Issue Date:: 1996-01-01

Research Org.:: Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)

OSTI Identifier:: 870554

Patent Number(s):: 5545304

Assignee:: Battelle Memorial Institute (Richland, WA)

Patent Classifications (CPCs):: G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES

H - ELECTRICITY H01 - BASIC ELECTRIC ELEMENTS H01J - ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS

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G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
G01N27/44717 - {Arrangements for investigating the separated zones, e.g. localising zones}
G01N27/4473 - {by electric means}

H - ELECTRICITY H01 - BASIC ELECTRIC ELEMENTS H01J - ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
H01J49/025 - {Detectors specially adapted to particle spectrometers

Show less

DOE Contract Number:: AC06-76RL01830

Resource Type:: Patent

Country of Publication:: United States

Language:: English

Subject:: current; detector; pressure; sources; monitoring; separations; relates; application; involving; signal; arising; produced; electrospray; 100; torr; specifically; apparatus; method; detection; emitted; capillary; electrophoresis; liquid; chromatography; small-scale; separation; methods; provides; simple; diagnostic; quality; operation; source; liquid chromatograph; capillary electrophoresis; liquid chromatography; separation method; scale separation; current detector; /204/73/250/

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                    Smith, Richard D, Wahl, Jon H, and Hofstadler, Steven A. Ion current detector for high pressure ion sources for monitoring separations.  United States: N. p., 1996. 
        Web.

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                    Smith, Richard D, Wahl, Jon H, & Hofstadler, Steven A. Ion current detector for high pressure ion sources for monitoring separations.  United States.

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                    Smith, Richard D, Wahl, Jon H, and Hofstadler, Steven A. Mon .  
        "Ion current detector for high pressure ion sources for monitoring separations".  United States.  https://www.osti.gov/servlets/purl/870554.

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@article{osti_870554,

  title        = {Ion current detector for high pressure ion sources for monitoring separations},

  author       = {Smith, Richard D and Wahl, Jon H and Hofstadler, Steven A},

  abstractNote = {The present invention relates generally to any application involving the monitoring of signal arising from ions produced by electrospray or other high pressure (>100 torr) ion sources. The present invention relates specifically to an apparatus and method for the detection of ions emitted from a capillary electrophoresis (CE) system, liquid chromatography, or other small-scale separation methods. And further, the invention provides a very simple diagnostic as to the quality of the separation and the operation of an electrospray source.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {1996},

  month        = {1}

}

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Ion current detector for high pressure ion sources for monitoring separations

Patent Smith, R D; Wahl, J H; Hofstadler, S A

The present invention relates generally to any application involving the monitoring of signal arising from ions produced by electrospray or other high pressure (>100 torr) ion sources. The present invention relates specifically to an apparatus and method for the detection of ions emitted from a capillary electrophoresis (CE) system, liquid chromatography, or other small-scale separation methods. And further, the invention provides a very simple diagnostic as to the quality of the separation and the operation of an electrospray source. 7 figs.
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