Noise suppressing capillary separation system
Abstract
A noise-suppressing capillary separation system for detecting the real-time presence or concentration of an analyte in a sample is provided. The system contains a capillary separation means through which the analyte is moved, a coherent light source that generates a beam which is split into a reference beam and a sample beam that irradiate the capillary, and a detector for detecting the reference beam and the sample beam light that transmits through the capillary. The laser beam is of a wavelength effective to be absorbed by a chromophore in the capillary. The system includes a noise suppressing system to improve performance and accuracy without signal averaging or multiple scans.
- Inventors:
-
- Ames, IA
- Norwich, NY
- Issue Date:
- Research Org.:
- Ames Laboratory (AMES), Ames, IA; Iowa State Univ., Ames, IA (United States)
- OSTI Identifier:
- 870536
- Patent Number(s):
- 5540825
- Application Number:
- 08/406,714
- Assignee:
- Iowa State University Research Foundation, Inc. (Ames, IA)
- Patent Classifications (CPCs):
-
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- W-7405-ENG-82
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- noise; suppressing; capillary; separation; noise-suppressing; detecting; real-time; presence; concentration; analyte; sample; provided; contains; means; moved; coherent; light; source; generates; beam; split; reference; irradiate; detector; transmits; laser; wavelength; effective; absorbed; chromophore; improve; performance; accuracy; signal; averaging; multiple; scans; reference beam; light source; laser beam; coherent light; sample beam; separation means; wavelength effective; beam light; capillary separation; improve performance; suppressing capillary; /204/73/356/
Citation Formats
Yeung, Edward S, and Xue, Yongjun. Noise suppressing capillary separation system. United States: N. p., 1996.
Web.
Yeung, Edward S, & Xue, Yongjun. Noise suppressing capillary separation system. United States.
Yeung, Edward S, and Xue, Yongjun. Mon .
"Noise suppressing capillary separation system". United States. https://www.osti.gov/servlets/purl/870536.
@article{osti_870536,
title = {Noise suppressing capillary separation system},
author = {Yeung, Edward S and Xue, Yongjun},
abstractNote = {A noise-suppressing capillary separation system for detecting the real-time presence or concentration of an analyte in a sample is provided. The system contains a capillary separation means through which the analyte is moved, a coherent light source that generates a beam which is split into a reference beam and a sample beam that irradiate the capillary, and a detector for detecting the reference beam and the sample beam light that transmits through the capillary. The laser beam is of a wavelength effective to be absorbed by a chromophore in the capillary. The system includes a noise suppressing system to improve performance and accuracy without signal averaging or multiple scans.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1996},
month = {1}
}
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