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Title: Biosensor and chemical sensor probes for calcium and other metal ions

Abstract

The present invention relates to chemical sensor and biosensor probes for measuring low concentration of metals and metal ions in complex samples such as biological fluids, living cells, and environmental samples. More particularly the present invention relates to a gel-based Indo-1 and Fura-2 chemical sensor probes for the measurement of low concentrations of calcium, cadmium, magnesium and the like. Also disclosed is a detector device using the sensors of the present invention.

Inventors:
 [1];  [2]
  1. Knoxville, TN
  2. Perpignan, FR
Issue Date:
Research Org.:
Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
OSTI Identifier:
870326
Patent Number(s):
5496522
Assignee:
Martin Marietta Energy Systems, Inc. (Oak Ridge, TN)
Patent Classifications (CPCs):
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
DOE Contract Number:  
AC05-84OR21400
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
biosensor; chemical; sensor; probes; calcium; metal; relates; measuring; concentration; metals; complex; samples; biological; fluids; living; cells; environmental; particularly; gel-based; indo-1; fura-2; measurement; concentrations; cadmium; magnesium; disclosed; detector; device; sensors; living cells; environmental sample; chemical sensor; environmental samples; biological fluids; sensor probe; biological fluid; sensor probes; detector device; /422/436/999/

Citation Formats

Vo-Dinh, Tuan, and Viallet, Pierre. Biosensor and chemical sensor probes for calcium and other metal ions. United States: N. p., 1996. Web.
Vo-Dinh, Tuan, & Viallet, Pierre. Biosensor and chemical sensor probes for calcium and other metal ions. United States.
Vo-Dinh, Tuan, and Viallet, Pierre. Mon . "Biosensor and chemical sensor probes for calcium and other metal ions". United States. https://www.osti.gov/servlets/purl/870326.
@article{osti_870326,
title = {Biosensor and chemical sensor probes for calcium and other metal ions},
author = {Vo-Dinh, Tuan and Viallet, Pierre},
abstractNote = {The present invention relates to chemical sensor and biosensor probes for measuring low concentration of metals and metal ions in complex samples such as biological fluids, living cells, and environmental samples. More particularly the present invention relates to a gel-based Indo-1 and Fura-2 chemical sensor probes for the measurement of low concentrations of calcium, cadmium, magnesium and the like. Also disclosed is a detector device using the sensors of the present invention.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1996},
month = {1}
}

Patent:

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