Biosensor and chemical sensor probes for calcium and other metal ions

Vo-Dinh, Tuan; Viallet, Pierre

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Title: Biosensor and chemical sensor probes for calcium and other metal ions

Abstract

The present invention relates to chemical sensor and biosensor probes for measuring low concentration of metals and metal ions in complex samples such as biological fluids, living cells, and environmental samples. More particularly the present invention relates to a gel-based Indo-1 and Fura-2 chemical sensor probes for the measurement of low concentrations of calcium, cadmium, magnesium and the like. Also disclosed is a detector device using the sensors of the present invention.

Inventors:

Vo-Dinh, Tuan ^[1]; Viallet, Pierre ^[2]

Knoxville, TN
Perpignan, FR

Issue Date:: 1996-01-01

Research Org.:: Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)

OSTI Identifier:: 870326

Patent Number(s):: 5496522

Assignee:: Martin Marietta Energy Systems, Inc. (Oak Ridge, TN)

Patent Classifications (CPCs):: G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES

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G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
G01N21/643 - {non-biological material}
G01N21/648 - {using evanescent coupling or surface plasmon coupling for the excitation of fluorescence}
G01N21/7703 - {using reagent-clad optical fibres or optical waveguides

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DOE Contract Number:: AC05-84OR21400

Resource Type:: Patent

Country of Publication:: United States

Language:: English

Subject:: biosensor; chemical; sensor; probes; calcium; metal; relates; measuring; concentration; metals; complex; samples; biological; fluids; living; cells; environmental; particularly; gel-based; indo-1; fura-2; measurement; concentrations; cadmium; magnesium; disclosed; detector; device; sensors; living cells; environmental sample; chemical sensor; environmental samples; biological fluids; sensor probe; biological fluid; sensor probes; detector device; /422/436/999/

Citation Formats


                    Vo-Dinh, Tuan, and Viallet, Pierre. Biosensor and chemical sensor probes for calcium and other metal ions.  United States: N. p., 1996. 
        Web.

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                    Vo-Dinh, Tuan, & Viallet, Pierre. Biosensor and chemical sensor probes for calcium and other metal ions.  United States.

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                    Vo-Dinh, Tuan, and Viallet, Pierre. Mon .  
        "Biosensor and chemical sensor probes for calcium and other metal ions".  United States.  https://www.osti.gov/servlets/purl/870326.

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@article{osti_870326,

  title        = {Biosensor and chemical sensor probes for calcium and other metal ions},

  author       = {Vo-Dinh, Tuan and Viallet, Pierre},

  abstractNote = {The present invention relates to chemical sensor and biosensor probes for measuring low concentration of metals and metal ions in complex samples such as biological fluids, living cells, and environmental samples. More particularly the present invention relates to a gel-based Indo-1 and Fura-2 chemical sensor probes for the measurement of low concentrations of calcium, cadmium, magnesium and the like. Also disclosed is a detector device using the sensors of the present invention.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {1996},

  month        = {1}

}

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Works referenced in this record:

New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures
journal, May 1980

Tsien, Roger Y.
Biochemistry, Vol. 19, Issue 11
https://doi.org/10.1021/bi00552a018

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Similar Records

Title: Biosensor and chemical sensor probes for calcium and other metal ions

Abstract

Citation Formats

New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures journal, May 1980

New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures
journal, May 1980