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Title: Biomarkers of cell senescence

The present invention provides a biomarker system for the in vivo and in vitro assessment of cell senescence. In the method of the present invention, .beta.-galactosidase activity is utilized as a means by which cell senescence may be assessed either in in vitro cell cultures or in vivo.
Inventors:
 [1];  [2];  [3]
  1. (Simli U.P., IN)
  2. (Berkeley, CA)
  3. (Newton, MA)
Issue Date:
OSTI Identifier:
870293
Assignee:
Regents of University of California (Oakland, CA) LBNL
Patent Number(s):
US 5491069
Contract Number:
AC03-76SF00098
Research Org:
Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA
Country of Publication:
United States
Language:
English
Subject:
biomarkers; cell; senescence; provides; biomarker; vivo; vitro; assessment; method; beta; -galactosidase; activity; utilized; means; assessed; cultures; cell senescence; cell culture; cell cultures; vitro assessment; vitro cell; -galactosidase activity; /435/436/

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