Colloidal-gold electrosensor measuring device
Abstract
The present invention provides a new device for use in measuring lead levels in biological and environmental samples. Using square wave coulometry and colloidal gold particles impregnated on carbon electrodes, the present invention provides a rapid, reliable, portable and inexpensive means of detecting low lead levels. The colloidal gold modified electrodes have microelectrode array characteristics and produce significantly higher stripping detection signals for lead than are produced at bulk gold electrode surfaces. The method is effective in determining levels of lead down to at least 5 .mu.g/dL in blood samples as small as 10 .mu.L.
- Inventors:
-
- Chapel Hill, NC
- Durham, NC
- Cary, NC
- Carrboro, NC
- Issue Date:
- Research Org.:
- Andcare, Inc. (Durham, NC)
- OSTI Identifier:
- 870163
- Patent Number(s):
- 5468366
- Assignee:
- Andcare, Inc. (Durham, NC)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- FG05-94ER81657
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- colloidal-gold; electrosensor; measuring; device; provides; lead; levels; biological; environmental; samples; square; wave; coulometry; colloidal; gold; particles; impregnated; carbon; electrodes; rapid; reliable; portable; inexpensive; means; detecting; modified; microelectrode; array; characteristics; produce; significantly; stripping; detection; signals; produced; bulk; electrode; surfaces; method; effective; determining; dl; blood; 10; carbon electrode; blood sample; blood samples; environmental sample; detection signals; electrode array; measuring device; electrode surface; environmental samples; square wave; carbon electrodes; microelectrode array; measuring lead; electrode surfaces; detection signal; inexpensive means; /205/204/435/436/
Citation Formats
Wegner, Steven, Harpold, Michael A, McCaffrey, Terence M, Morris, Susan E, Wojciechowski, Marek, Zhao, Junguo, Henkens, Robert W, Naser, Najih, and O'Daly, John P. Colloidal-gold electrosensor measuring device. United States: N. p., 1995.
Web.
Wegner, Steven, Harpold, Michael A, McCaffrey, Terence M, Morris, Susan E, Wojciechowski, Marek, Zhao, Junguo, Henkens, Robert W, Naser, Najih, & O'Daly, John P. Colloidal-gold electrosensor measuring device. United States.
Wegner, Steven, Harpold, Michael A, McCaffrey, Terence M, Morris, Susan E, Wojciechowski, Marek, Zhao, Junguo, Henkens, Robert W, Naser, Najih, and O'Daly, John P. Sun .
"Colloidal-gold electrosensor measuring device". United States. https://www.osti.gov/servlets/purl/870163.
@article{osti_870163,
title = {Colloidal-gold electrosensor measuring device},
author = {Wegner, Steven and Harpold, Michael A and McCaffrey, Terence M and Morris, Susan E and Wojciechowski, Marek and Zhao, Junguo and Henkens, Robert W and Naser, Najih and O'Daly, John P},
abstractNote = {The present invention provides a new device for use in measuring lead levels in biological and environmental samples. Using square wave coulometry and colloidal gold particles impregnated on carbon electrodes, the present invention provides a rapid, reliable, portable and inexpensive means of detecting low lead levels. The colloidal gold modified electrodes have microelectrode array characteristics and produce significantly higher stripping detection signals for lead than are produced at bulk gold electrode surfaces. The method is effective in determining levels of lead down to at least 5 .mu.g/dL in blood samples as small as 10 .mu.L.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Sun Jan 01 00:00:00 EST 1995},
month = {Sun Jan 01 00:00:00 EST 1995}
}
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