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Title: Colloidal-gold electrosensor measuring device

Abstract

The present invention provides a new device for use in measuring lead levels in biological and environmental samples. Using square wave coulometry and colloidal gold particles impregnated on carbon electrodes, the present invention provides a rapid, reliable, portable and inexpensive means of detecting low lead levels. The colloidal gold modified electrodes have microelectrode array characteristics and produce significantly higher stripping detection signals for lead than are produced at bulk gold electrode surfaces. The method is effective in determining levels of lead down to at least 5 .mu.g/dL in blood samples as small as 10 .mu.L.

Inventors:
 [1];  [2];  [2];  [1];  [3];  [1];  [2];  [2];  [4]
  1. Chapel Hill, NC
  2. Durham, NC
  3. Cary, NC
  4. Carrboro, NC
Issue Date:
Research Org.:
Andcare, Inc. (Durham, NC)
OSTI Identifier:
870163
Patent Number(s):
5468366
Assignee:
Andcare, Inc. (Durham, NC)
DOE Contract Number:  
FG05-94ER81657
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
colloidal-gold; electrosensor; measuring; device; provides; lead; levels; biological; environmental; samples; square; wave; coulometry; colloidal; gold; particles; impregnated; carbon; electrodes; rapid; reliable; portable; inexpensive; means; detecting; modified; microelectrode; array; characteristics; produce; significantly; stripping; detection; signals; produced; bulk; electrode; surfaces; method; effective; determining; dl; blood; 10; carbon electrode; blood sample; blood samples; environmental sample; detection signals; electrode array; measuring device; electrode surface; environmental samples; square wave; carbon electrodes; microelectrode array; measuring lead; electrode surfaces; detection signal; inexpensive means; /205/204/435/436/

Citation Formats

Wegner, Steven, Harpold, Michael A, McCaffrey, Terence M, Morris, Susan E, Wojciechowski, Marek, Zhao, Junguo, Henkens, Robert W, Naser, Najih, and O'Daly, John P. Colloidal-gold electrosensor measuring device. United States: N. p., 1995. Web.
Wegner, Steven, Harpold, Michael A, McCaffrey, Terence M, Morris, Susan E, Wojciechowski, Marek, Zhao, Junguo, Henkens, Robert W, Naser, Najih, & O'Daly, John P. Colloidal-gold electrosensor measuring device. United States.
Wegner, Steven, Harpold, Michael A, McCaffrey, Terence M, Morris, Susan E, Wojciechowski, Marek, Zhao, Junguo, Henkens, Robert W, Naser, Najih, and O'Daly, John P. Sun . "Colloidal-gold electrosensor measuring device". United States. https://www.osti.gov/servlets/purl/870163.
@article{osti_870163,
title = {Colloidal-gold electrosensor measuring device},
author = {Wegner, Steven and Harpold, Michael A and McCaffrey, Terence M and Morris, Susan E and Wojciechowski, Marek and Zhao, Junguo and Henkens, Robert W and Naser, Najih and O'Daly, John P},
abstractNote = {The present invention provides a new device for use in measuring lead levels in biological and environmental samples. Using square wave coulometry and colloidal gold particles impregnated on carbon electrodes, the present invention provides a rapid, reliable, portable and inexpensive means of detecting low lead levels. The colloidal gold modified electrodes have microelectrode array characteristics and produce significantly higher stripping detection signals for lead than are produced at bulk gold electrode surfaces. The method is effective in determining levels of lead down to at least 5 .mu.g/dL in blood samples as small as 10 .mu.L.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1995},
month = {1}
}

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