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Title: Loading and conjugating cavity biostructures

Methods for the preparation and use of a biological delivery system are disclosed. The method of preparation includes the loading of a non-biological material into a biostructure having a load-bearing structure. The method also includes the removal of some of the biostructure's contents and the loading of a non-biological material into the biostructure. The biostructure is biologically compatible with the host, and preferably is derived from the host, the host's species or a related species. The loaded biostructure is used directly, or it can be targeted to specific cells, tissues and/or organs within a host. The targeted biostructure can be used to deliver the non-biological material to a specified tissue, organ or cell within a host for diagnostic, therapeutic or other purposes.
  1. (Shoreham, NY)
Issue Date:
OSTI Identifier:
Associated Universities, Inc. (Washington, DC) BNL
Patent Number(s):
US 5443813
Application Number:
Contract Number:
Research Org:
Country of Publication:
United States
loading; conjugating; cavity; biostructures; methods; preparation; biological; delivery; disclosed; method; non-biological; material; biostructure; load-bearing; structure; removal; contents; biologically; compatible; host; preferably; derived; species; related; loaded; directly; targeted; specific; cells; tissues; organs; deliver; specified; tissue; organ; cell; diagnostic; therapeutic; purposes; non-biological material; specific cells; biological material; cavity biostructures; bearing structure; biological delivery; conjugating cavity; load-bearing structure; /424/530/