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Title: Self-regenerating column chromatography

The present invention provides a process for treating both cations and anions by using a self-regenerating, multi-ionic exchange resin column system which requires no separate regeneration steps. The process involves alternating ion-exchange chromatography for cations and anions in a multi-ionic exchange column packed with a mixture of cation and anion exchange resins. The multi-ionic mixed-charge resin column works as a multi-function column, capable of independently processing either cationic or anionic exchange, or simultaneously processing both cationic and anionic exchanges. The major advantage offered by the alternating multi-function ion exchange process is the self-regeneration of the resins.
  1. (Centerville, OH)
Issue Date:
OSTI Identifier:
United States of America as represented by United States (Washington, DC) ALO
Patent Number(s):
US 5419819
Application Number:
Contract Number:
Research Org:
Monsanto Research Corporation
Sponsoring Org:
Country of Publication:
United States
self-regenerating; column; chromatography; provides; process; treating; cations; anions; multi-ionic; exchange; resin; requires; separate; regeneration; steps; involves; alternating; ion-exchange; packed; mixture; cation; anion; resins; mixed-charge; multi-function; capable; independently; processing; cationic; anionic; simultaneously; exchanges; major; advantage; offered; self-regeneration; exchange column; anion exchange; process involves; exchange resin; exchange resins; column chromatography; exchange process; exchange chromatography; regeneration step; /204/376/