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Title: Instrument for the application of controlled mechanical loads to tissues in sterile culture

Abstract

Apparatus and methods are disclosed facilitating the application of forces and measurement of dimensions of a test subject. In one arrangement the test subject is coupled to a forcing frame and controlled forces applied thereto by a series of guideways and sliders. The sliders, which contact the test subject are in force transmitting relation to a forcing frame. Tension, compression and bending forces can be applied to the test subject. Force applied to the test subject is measured and controlled. A dimensional characteristic of the test subject, such as growth, is measured by a linear variable differential transformer. The growth measurement data can be used to control the force applied. Substantially uniaxial stretching is achieved by placing the test subject on an elastic membrane stretched by an arrangement of members securing the elastic member to the forcing frame.

Inventors:
 [1];  [2]
  1. Shelburne, VT
  2. Essex Junction, VT
Issue Date:
Research Org.:
Liveco Inc
OSTI Identifier:
869837
Patent Number(s):
5406853
Assignee:
John Chatillon & Sons, Inc. (Greensboro, NC)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12M - APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
DOE Contract Number:  
AC02-86ER80373
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
instrument; application; controlled; mechanical; loads; tissues; sterile; culture; apparatus; methods; disclosed; facilitating; forces; measurement; dimensions; subject; arrangement; coupled; forcing; frame; applied; thereto; series; guideways; sliders; contact; force; transmitting; relation; tension; compression; bending; measured; dimensional; characteristic; growth; linear; variable; differential; transformer; data; control; substantially; uniaxial; stretching; achieved; placing; elastic; membrane; stretched; securing; applied thereto; force applied; differential transformer; forces applied; variable differential; linear variable; mechanical loads; measurement data; transmitting relation; mechanical load; elastic membrane; disclosed facilitating; /73/435/

Citation Formats

Lintilhac, Phillip M, and Vesecky, Thompson B. Instrument for the application of controlled mechanical loads to tissues in sterile culture. United States: N. p., 1995. Web.
Lintilhac, Phillip M, & Vesecky, Thompson B. Instrument for the application of controlled mechanical loads to tissues in sterile culture. United States.
Lintilhac, Phillip M, and Vesecky, Thompson B. Sun . "Instrument for the application of controlled mechanical loads to tissues in sterile culture". United States. https://www.osti.gov/servlets/purl/869837.
@article{osti_869837,
title = {Instrument for the application of controlled mechanical loads to tissues in sterile culture},
author = {Lintilhac, Phillip M and Vesecky, Thompson B},
abstractNote = {Apparatus and methods are disclosed facilitating the application of forces and measurement of dimensions of a test subject. In one arrangement the test subject is coupled to a forcing frame and controlled forces applied thereto by a series of guideways and sliders. The sliders, which contact the test subject are in force transmitting relation to a forcing frame. Tension, compression and bending forces can be applied to the test subject. Force applied to the test subject is measured and controlled. A dimensional characteristic of the test subject, such as growth, is measured by a linear variable differential transformer. The growth measurement data can be used to control the force applied. Substantially uniaxial stretching is achieved by placing the test subject on an elastic membrane stretched by an arrangement of members securing the elastic member to the forcing frame.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1995},
month = {1}
}

Works referenced in this record:

An apparatus for fatigue-testing of fibres
journal, November 1971