Gene for ataxia-telangiectasia complementation group D (ATDC)
Abstract
Disclosed herein is a new gene, an AT gene for complementation group D, the ATDC gene and fragments thereof. Nucleic acid probes for said gene are provided as well as proteins encoded by said gene, cDNA therefrom, preferably a 3 kilobase (kb) cDNA, and recombinant nucleic acid molecules for expression of said proteins. Further disclosed are methods to detect mutations in said gene, preferably methods employing the polymerase chain reaction (PCR). Also disclosed are methods to detect AT genes from other AT complementation groups.
- Inventors:
-
- San Francisco, CA
- Burlingame, CA
- San Rafael, CA
- Redwood City, CA
- Issue Date:
- Research Org.:
- Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 869776
- Patent Number(s):
- 5395767
- Assignee:
- Regents of University of California (California, CA)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
- DOE Contract Number:
- W-7405-ENG-48; AC03-76SF01012
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- ataxia-telangiectasia; complementation; atdc; disclosed; fragments; nucleic; acid; probes; provided; proteins; encoded; cdna; therefrom; preferably; kilobase; kb; recombinant; molecules; expression; methods; detect; mutations; employing; polymerase; chain; reaction; pcr; genes; acid molecule; chain reaction; acid probes; acid molecules; nucleic acid; polymerase chain; acid probe; methods employing; methods employ; /435/999/
Citation Formats
Murnane, John P, Painter, Robert B, Kapp, Leon N, and Yu, Loh-Chung. Gene for ataxia-telangiectasia complementation group D (ATDC). United States: N. p., 1995.
Web.
Murnane, John P, Painter, Robert B, Kapp, Leon N, & Yu, Loh-Chung. Gene for ataxia-telangiectasia complementation group D (ATDC). United States.
Murnane, John P, Painter, Robert B, Kapp, Leon N, and Yu, Loh-Chung. Tue .
"Gene for ataxia-telangiectasia complementation group D (ATDC)". United States. https://www.osti.gov/servlets/purl/869776.
@article{osti_869776,
title = {Gene for ataxia-telangiectasia complementation group D (ATDC)},
author = {Murnane, John P and Painter, Robert B and Kapp, Leon N and Yu, Loh-Chung},
abstractNote = {Disclosed herein is a new gene, an AT gene for complementation group D, the ATDC gene and fragments thereof. Nucleic acid probes for said gene are provided as well as proteins encoded by said gene, cDNA therefrom, preferably a 3 kilobase (kb) cDNA, and recombinant nucleic acid molecules for expression of said proteins. Further disclosed are methods to detect mutations in said gene, preferably methods employing the polymerase chain reaction (PCR). Also disclosed are methods to detect AT genes from other AT complementation groups.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1995},
month = {3}
}
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