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Title: Triamine chelants, their derivatives, complexes and conjugates

A group of functionalized triamine chelants and their derivatives that form complexes with radioactive metal ions are disclosed. The complexes can be covalently attached to a protein or an antibody or antibody fragment and used for therapeutic and/or diagnostic purposes. The chelants are of the formula: ##STR1## wherein n, m, R, R.sup.1, R.sup.2 and L are defined in the specification.
 [1];  [2];  [3]
  1. (Phoenixville, PA)
  2. (Gaithersburg, MD)
  3. (Vashi, IN)
Issue Date:
OSTI Identifier:
Curators of University of Missouri (Columbia, MO) CHO
Patent Number(s):
US 5395608
Contract Number:
Research Org:
University of Missouri
Country of Publication:
United States
triamine; chelants; derivatives; complexes; conjugates; functionalized; form; radioactive; metal; disclosed; covalently; attached; protein; antibody; fragment; therapeutic; diagnostic; purposes; formula; str1; defined; specification; radioactive metal; active metal; triamine chelants; antibody fragment; diagnostic purposes; covalently attached; functionalized triamine; form complexes; /424/530/999/