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Title: Triamine chelants, their derivatives, complexes and conjugates

Abstract

A group of functionalized triamine chelants and their derivatives that form complexes with radioactive metal ions are disclosed. The complexes can be covalently attached to a protein or an antibody or antibody fragment and used for therapeutic and/or diagnostic purposes. The chelants are of the formula: ##STR1## wherein n, m, R, R.sup.1, R.sup.2 and L are defined in the specification.

Inventors:
 [1];  [2];  [3]
  1. Phoenixville, PA
  2. Gaithersburg, MD
  3. Vashi, IN
Issue Date:
Research Org.:
Univ. of Missouri, Columbia, MO (United States)
OSTI Identifier:
869774
Patent Number(s):
5395608
Assignee:
Curators of University of Missouri (Columbia, MO)
DOE Contract Number:  
FG02-86ER60400
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
triamine; chelants; derivatives; complexes; conjugates; functionalized; form; radioactive; metal; disclosed; covalently; attached; protein; antibody; fragment; therapeutic; diagnostic; purposes; formula; str1; defined; specification; radioactive metal; active metal; triamine chelants; antibody fragment; diagnostic purposes; covalently attached; functionalized triamine; form complexes; /424/530/999/

Citation Formats

Troutner, David E, John, Christy S, and Pillai, Maroor R. A. Triamine chelants, their derivatives, complexes and conjugates. United States: N. p., 1995. Web.
Troutner, David E, John, Christy S, & Pillai, Maroor R. A. Triamine chelants, their derivatives, complexes and conjugates. United States.
Troutner, David E, John, Christy S, and Pillai, Maroor R. A. Sun . "Triamine chelants, their derivatives, complexes and conjugates". United States. https://www.osti.gov/servlets/purl/869774.
@article{osti_869774,
title = {Triamine chelants, their derivatives, complexes and conjugates},
author = {Troutner, David E and John, Christy S and Pillai, Maroor R. A.},
abstractNote = {A group of functionalized triamine chelants and their derivatives that form complexes with radioactive metal ions are disclosed. The complexes can be covalently attached to a protein or an antibody or antibody fragment and used for therapeutic and/or diagnostic purposes. The chelants are of the formula: ##STR1## wherein n, m, R, R.sup.1, R.sup.2 and L are defined in the specification.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1995},
month = {1}
}

Patent:

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