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Title: Process for the preparation of 3,4-dihydroxybutanoic acid and salts thereof

A process for the preparation of 3,4-dihydroxybutanoic acid (1) and salts thereof from a glucose source containing 1,4-1inked glucose as a substituent is described. The process uses an alkali metal hdyroxide and hydrogen peroxide to convert the glucose source to (1). The compound (1) is useful as a chemical intermediate to naturally occurring fatty acids and is used to prepare 3,4-dihydroxybutanoic acid-gamma-lactone (2) and furanone (3), particularly stereoisomers of these compounds.
  1. (Haslett, MI)
Issue Date:
OSTI Identifier:
Board of Trustees operating Michigan State University (East Lansing, MI) CHO
Patent Number(s):
US 5374773
Contract Number:
Research Org:
Michigan State Univ., East Lansing, MI (United States)
Country of Publication:
United States
process; preparation; 4-dihydroxybutanoic; acid; salts; glucose; source; containing; 4-1inked; substituent; described; alkali; metal; hdyroxide; hydrogen; peroxide; convert; compound; useful; chemical; intermediate; naturally; occurring; fatty; acids; prepare; acid-gamma-lactone; furanone; particularly; stereoisomers; compounds; fatty acids; hydrogen peroxide; naturally occurring; alkali metal; fatty acid; source containing; glucose source; chemical intermediate; anoic acid; /999/