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Title: Vaccine to control the viral infection of fish

Abstract

Subunit vaccines and their use for immunizing fish against infection by viruses are disclosed. In particular, plasmid pG8 is constructed by joining, with the plasmid pUC8, DNA which encodes the glycoprotein of infectious hematopoietic necrosis virus (IHNV). E. coli cells are transformed by pG8, whereby pure viral antigen is produced to provide a vaccine for the control of IHNV in fish.

Inventors:
 [1]
  1. Albany, OR
Issue Date:
Research Org.:
Oregon State Univ., Corvallis, OR (United States)
OSTI Identifier:
869546
Patent Number(s):
5354555
Application Number:
08/027,742
Assignee:
State of Oregon Acting By and Through State Board of Higher (Eugene, OR)
Patent Classifications (CPCs):
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10S - TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
DOE Contract Number:  
AI79-84BP16479
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
vaccine; control; viral; infection; fish; subunit; vaccines; immunizing; viruses; disclosed; particular; plasmid; pg8; constructed; joining; puc8; dna; encodes; glycoprotein; infectious; hematopoietic; necrosis; virus; ihnv; coli; cells; transformed; whereby; pure; antigen; produced; provide; viral infection; /424/435/

Citation Formats

Leong, Jo-Ann C. Vaccine to control the viral infection of fish. United States: N. p., 1994. Web.
Leong, Jo-Ann C. Vaccine to control the viral infection of fish. United States.
Leong, Jo-Ann C. Tue . "Vaccine to control the viral infection of fish". United States. https://www.osti.gov/servlets/purl/869546.
@article{osti_869546,
title = {Vaccine to control the viral infection of fish},
author = {Leong, Jo-Ann C},
abstractNote = {Subunit vaccines and their use for immunizing fish against infection by viruses are disclosed. In particular, plasmid pG8 is constructed by joining, with the plasmid pUC8, DNA which encodes the glycoprotein of infectious hematopoietic necrosis virus (IHNV). E. coli cells are transformed by pG8, whereby pure viral antigen is produced to provide a vaccine for the control of IHNV in fish.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1994},
month = {10}
}

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Works referenced in this record:

Rabies virus glycoprotein analogs: biosynthesis in Escherichia coli
journal, February 1983


A comparison of detection methods for infectious haematopoietic necrosis virus
journal, January 1985


Physico-chemical and Serological Characterization of Five Rhabdoviruses Infecting Fish
journal, June 1975


Expression in Escherichia Coli of an Epitope of the Glycoprotein of Infectious Hematopoietic Necrosis Virus Protects Against Viral Challenge
journal, March 1988


Expression of rabies virus glycoprotein from a recombinant vaccinia virus
journal, November 1984


Transcription in vitro of Infectious Haematopoietic Necrosis Virus, a Fish Rhabdovirus
journal, June 1987


Rabies Subunit Vaccines
journal, August 1983


Virion RNA polymerases of two salmonid rhabdoviruses
journal, June 1977


Antibody diversity in lower vertebrates—why is it so restricted?
journal, March 1982