skip to main content
DOE Patents title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Multiplexed fluorescence detector system for capillary electrophoresis

Abstract

A fluorescence detection system for capillary electrophoresis is provided wherein the detection system can simultaneously excite fluorescence and substantially simultaneously monitor separations in multiple capillaries. This multiplexing approach involves laser irradiation of a sample in a plurality of capillaries through optical fibers that are coupled individually with the capillaries. The array is imaged orthogonally through a microscope onto a charge-coupled device camera for signal analysis.

Inventors:
 [1];  [2]
  1. (Ames, IA)
  2. (Nevada, IA)
Issue Date:
Research Org.:
Ames Laboratory (AMES), Ames, IA; Iowa State University, Ames, IA (US)
OSTI Identifier:
869367
Patent Number(s):
5324401
Application Number:
08/013,960
Assignee:
Iowa State University Research Foundation, Inc. (Ames, IA) AMES
DOE Contract Number:  
W-7405-ENG-82
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
multiplexed; fluorescence; detector; capillary; electrophoresis; detection; provided; simultaneously; excite; substantially; monitor; separations; multiple; capillaries; multiplexing; approach; involves; laser; irradiation; sample; plurality; optical; fibers; coupled; individually; array; imaged; orthogonally; microscope; charge-coupled; device; camera; signal; analysis; fluorescence detection; charge-coupled device; multiple capillaries; laser irradiation; coupled device; substantially simultaneously; capillary electrophoresis; optical fibers; optical fiber; signal analysis; approach involves; fluorescence detector; simultaneously monitor; simultaneously excite; multiplexed fluorescence; device camera; excite fluorescence; substantially simultaneous; /204/356/

Citation Formats

Yeung, Edward S., and Taylor, John A. Multiplexed fluorescence detector system for capillary electrophoresis. United States: N. p., 1994. Web.
Yeung, Edward S., & Taylor, John A. Multiplexed fluorescence detector system for capillary electrophoresis. United States.
Yeung, Edward S., and Taylor, John A. Tue . "Multiplexed fluorescence detector system for capillary electrophoresis". United States. https://www.osti.gov/servlets/purl/869367.
@article{osti_869367,
title = {Multiplexed fluorescence detector system for capillary electrophoresis},
author = {Yeung, Edward S. and Taylor, John A.},
abstractNote = {A fluorescence detection system for capillary electrophoresis is provided wherein the detection system can simultaneously excite fluorescence and substantially simultaneously monitor separations in multiple capillaries. This multiplexing approach involves laser irradiation of a sample in a plurality of capillaries through optical fibers that are coupled individually with the capillaries. The array is imaged orthogonally through a microscope onto a charge-coupled device camera for signal analysis.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1994},
month = {6}
}

Patent:

Save / Share: