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Title: Method for detection of antibodies for metallic elements

An apparatus and method for detecting antibodies specific to non-protein antigens. The apparatus is an immunological plate containing a plurality of plastic projections coated with a non-protein material. Assays utilizing the plate are capable of stabilizing the non-protein antigens with detection levels for antibodies specific to the antigens on a nanogram level. A screening assay with the apparatus allows for early detection of exposure to non-protein materials. Specifically metallic elements are detected.
Inventors:
 [1];  [2];  [1]
  1. (Golden, CO)
  2. (Larkspur, CO)
Issue Date:
OSTI Identifier:
869042
Assignee:
United States of America as represented by United States (Washington, DC) SNL
Patent Number(s):
US 5266499
Application Number:
07/856,105
Contract Number:
AC04-76DP03533
Research Org:
ROCKWELL INTERNATIONAL CORP
Country of Publication:
United States
Language:
English
Subject:
method; detection; antibodies; metallic; elements; apparatus; detecting; specific; non-protein; antigens; immunological; plate; containing; plurality; plastic; projections; coated; material; assays; utilizing; capable; stabilizing; levels; nanogram; level; screening; assay; allows; exposure; materials; specifically; detected; plate containing; nanogram level; apparatus allows; metallic elements; antibodies specific; metallic element; /436/422/