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Title: No-carrier-added (NCA) aryl (18E) fluorides via the nucleophilic aromatic substitution of electron rich aromatic rings

Abstract

A method for synthesizing no-carrier-added (NCA) aryl [.sup.18 F] fluoride substituted aromatic aldehyde compositions bearing an electron donating group is described. The method of the present invention includes the step of reacting aromatic nitro aldehydes having a suitably protected hydroxyl substitutent on an electron rich ring. The reaction is The U.S. Government has rights in this invention pursuant to Contract Number DE-AC02-76CH00016, between the U.S. Department of Energy and Associated Universities Inc.

Inventors:
 [1];  [2];  [3]
  1. (Central Islip, NY)
  2. (Bellport, NY)
  3. (Setauket, NY)
Issue Date:
Research Org.:
ASSOC UNIVERSITIES INC
OSTI Identifier:
868971
Patent Number(s):
5254726
Assignee:
United States of America as represented by Department of Energy (Washington, DC) BNL
DOE Contract Number:  
AC02-76CH00016
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
no-carrier-added; nca; aryl; 18e; fluorides; via; nucleophilic; aromatic; substitution; electron; rich; rings; method; synthesizing; 18; fluoride; substituted; aldehyde; compositions; bearing; donating; described; step; reacting; nitro; aldehydes; suitably; protected; hydroxyl; substitutent; reaction; government; rights; pursuant; contract; de-ac02-76ch00016; department; energy; associated; universities; associated universities; substituted aromatic; aromatic rings; /999/

Citation Formats

Ding, Yu-Shin, Fowler, Joanna S., and Wolf, Alfred P. No-carrier-added (NCA) aryl (18E) fluorides via the nucleophilic aromatic substitution of electron rich aromatic rings. United States: N. p., 1993. Web.
Ding, Yu-Shin, Fowler, Joanna S., & Wolf, Alfred P. No-carrier-added (NCA) aryl (18E) fluorides via the nucleophilic aromatic substitution of electron rich aromatic rings. United States.
Ding, Yu-Shin, Fowler, Joanna S., and Wolf, Alfred P. Fri . "No-carrier-added (NCA) aryl (18E) fluorides via the nucleophilic aromatic substitution of electron rich aromatic rings". United States. https://www.osti.gov/servlets/purl/868971.
@article{osti_868971,
title = {No-carrier-added (NCA) aryl (18E) fluorides via the nucleophilic aromatic substitution of electron rich aromatic rings},
author = {Ding, Yu-Shin and Fowler, Joanna S. and Wolf, Alfred P.},
abstractNote = {A method for synthesizing no-carrier-added (NCA) aryl [.sup.18 F] fluoride substituted aromatic aldehyde compositions bearing an electron donating group is described. The method of the present invention includes the step of reacting aromatic nitro aldehydes having a suitably protected hydroxyl substitutent on an electron rich ring. The reaction is The U.S. Government has rights in this invention pursuant to Contract Number DE-AC02-76CH00016, between the U.S. Department of Energy and Associated Universities Inc.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1993},
month = {1}
}

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