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Title: Means and method of detection in chemical separation procedures

Abstract

A means and method for indirect detection of constituent components of a mixture separated in a chemical separation process. Fluorescing ions are distributed across the area in which separation of the mixture will occur to provide a generally uniform background fluorescence intensity. For example, the mixture is comprised of one or more charged analytes which displace fluorescing ions where its constituent components separate to. Fluorescing ions of the same charge as the charged analyte components cause a displacement. The displacement results in the location of the separated components having a reduced fluorescence intensity to the remainder of the background. Detection of the lower fluorescence intensity areas can be visually, by photographic means and methods, or by automated laser scanning.

Inventors:
 [1];  [1];  [1];  [1];  [1]
  1. Ames, IA
Issue Date:
Research Org.:
Ames Laboratory (AMES), Ames, IA; Iowa State University, Ames, IA (US)
OSTI Identifier:
868691
Patent Number(s):
5192407
Application Number:
07/472,315
Assignee:
Iowa State University Research Foundation, Inc. (Ames, IA)
DOE Contract Number:  
W-7405-ENG-82
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
means; method; detection; chemical; separation; procedures; indirect; constituent; components; mixture; separated; process; fluorescing; distributed; occur; provide; uniform; background; fluorescence; intensity; example; comprised; charged; analytes; displace; separate; charge; analyte; displacement; results; location; reduced; remainder; visually; photographic; methods; automated; laser; scanning; direct detection; separation process; fluorescence intensity; separated components; chemical separation; laser scanning; constituent components; mixture separated; laser scan; /204/

Citation Formats

Yeung, Edward S, Koutny, Lance B, Hogan, Barry L, Cheung, Chan K, and Ma, Yinfa. Means and method of detection in chemical separation procedures. United States: N. p., 1993. Web.
Yeung, Edward S, Koutny, Lance B, Hogan, Barry L, Cheung, Chan K, & Ma, Yinfa. Means and method of detection in chemical separation procedures. United States.
Yeung, Edward S, Koutny, Lance B, Hogan, Barry L, Cheung, Chan K, and Ma, Yinfa. Tue . "Means and method of detection in chemical separation procedures". United States. https://www.osti.gov/servlets/purl/868691.
@article{osti_868691,
title = {Means and method of detection in chemical separation procedures},
author = {Yeung, Edward S and Koutny, Lance B and Hogan, Barry L and Cheung, Chan K and Ma, Yinfa},
abstractNote = {A means and method for indirect detection of constituent components of a mixture separated in a chemical separation process. Fluorescing ions are distributed across the area in which separation of the mixture will occur to provide a generally uniform background fluorescence intensity. For example, the mixture is comprised of one or more charged analytes which displace fluorescing ions where its constituent components separate to. Fluorescing ions of the same charge as the charged analyte components cause a displacement. The displacement results in the location of the separated components having a reduced fluorescence intensity to the remainder of the background. Detection of the lower fluorescence intensity areas can be visually, by photographic means and methods, or by automated laser scanning.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1993},
month = {3}
}

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