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Title: DNA Sequencing apparatus

Abstract

An automated DNA sequencing apparatus having a reactor for providing at least two series of DNA products formed from a single primer and a DNA strand, each DNA product of a series differing in molecular weight and having a chain terminating agent at one end; separating means for separating the DNA products to form a series bands, the intensity of substantially all nearby bands in a different series being different, band reading means for determining the position an This invention was made with government support including a grant from the U.S. Public Health Service, contract number AI-06045. The U.S. government has certain rights in the invention.

Inventors:
 [1];  [2]
  1. Cambridge, MA
  2. Chestnut Hill, MA
Issue Date:
Research Org.:
Harvard University
OSTI Identifier:
868349
Patent Number(s):
5122345
Assignee:
President and Fellows of Harvard College (Cambridge, MA)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10S - TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
DOE Contract Number:  
FG02-88ER60688
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
dna; sequencing; apparatus; automated; reactor; providing; series; products; formed; single; primer; strand; product; differing; molecular; weight; chain; terminating; agent; separating; means; form; bands; intensity; substantially; nearby; band; reading; determining; position; government; support; including; grant; public; health; service; contract; ai-06045; rights; dna strand; molecular weight; dna sequencing; government support; support including; sequencing apparatus; products formed; /422/204/

Citation Formats

Tabor, Stanley, and Richardson, Charles C. DNA Sequencing apparatus. United States: N. p., 1992. Web.
Tabor, Stanley, & Richardson, Charles C. DNA Sequencing apparatus. United States.
Tabor, Stanley, and Richardson, Charles C. Wed . "DNA Sequencing apparatus". United States. https://www.osti.gov/servlets/purl/868349.
@article{osti_868349,
title = {DNA Sequencing apparatus},
author = {Tabor, Stanley and Richardson, Charles C},
abstractNote = {An automated DNA sequencing apparatus having a reactor for providing at least two series of DNA products formed from a single primer and a DNA strand, each DNA product of a series differing in molecular weight and having a chain terminating agent at one end; separating means for separating the DNA products to form a series bands, the intensity of substantially all nearby bands in a different series being different, band reading means for determining the position an This invention was made with government support including a grant from the U.S. Public Health Service, contract number AI-06045. The U.S. government has certain rights in the invention.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1992},
month = {1}
}

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