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Title: Laser excited confocal microscope fluorescence scanner and method

Abstract

A fluorescent scanner for scanning the fluorescence from a fluorescence labeled separated sample on a sample carrier including a confocal microscope for illuminating a predetermined volume of the sample carrier and/or receiving and processing fluorescence emissions from said volume to provide a display of the separated sample.

Inventors:
 [1];  [1]
  1. Contra Costa, CA
Issue Date:
Research Org.:
Univ. of California (United States)
OSTI Identifier:
868178
Patent Number(s):
5091652
Assignee:
Regents of University of California (Oakland, CA)
Patent Classifications (CPCs):
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
G - PHYSICS G02 - OPTICS G02B - OPTICAL ELEMENTS, SYSTEMS, OR APPARATUS
DOE Contract Number:  
FG03-88ER60706
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
laser; excited; confocal; microscope; fluorescence; scanner; method; fluorescent; scanning; labeled; separated; sample; carrier; including; illuminating; predetermined; volume; receiving; processing; emissions; provide; display; confocal microscope; predetermined volume; fluorescence emission; fluorescence emissions; fluorescence scanner; /250/204/

Citation Formats

Mathies, Richard A, and Peck, Konan. Laser excited confocal microscope fluorescence scanner and method. United States: N. p., 1992. Web.
Mathies, Richard A, & Peck, Konan. Laser excited confocal microscope fluorescence scanner and method. United States.
Mathies, Richard A, and Peck, Konan. Wed . "Laser excited confocal microscope fluorescence scanner and method". United States. https://www.osti.gov/servlets/purl/868178.
@article{osti_868178,
title = {Laser excited confocal microscope fluorescence scanner and method},
author = {Mathies, Richard A and Peck, Konan},
abstractNote = {A fluorescent scanner for scanning the fluorescence from a fluorescence labeled separated sample on a sample carrier including a confocal microscope for illuminating a predetermined volume of the sample carrier and/or receiving and processing fluorescence emissions from said volume to provide a display of the separated sample.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Wed Jan 01 00:00:00 EST 1992},
month = {Wed Jan 01 00:00:00 EST 1992}
}

Works referenced in this record:

Non-radioactive automated sequencing of oligonucleotides by chemical degradation
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Fluorescence detection in automated DNA sequence analysis
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Optimization of high-sensitivity fluorescence detection
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Detection of single molecules of phycoerythrin in hydrodynamically focused flows by laser-induced fluorescence
journal, September 1987


Single-molecule fluorescence detection: autocorrelation criterion and experimental realization with phycoerythrin.
journal, June 1989


DNA sequencing with chain-terminating inhibitors
journal, December 1977


A stable double-stranded DNA-ethidium homodimer complex: application to picogram fluorescence detection of DNA in agarose gels.
journal, May 1990