Fiber optic detector for immuno-testing

Partin, Judy K; Ward, Thomas E; Grey, Alan E

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Title: Fiber optic detector for immuno-testing

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Abstract

A portable fiber optic detector that senses the presence of specific target chemicals in air or a gas by exchanging the target chemical for a fluoroescently-tagged antigen that is bound to an antibody which is in turn attached to an optical fiber. Replacing the fluorescently-tagged antigen reduces the fluorescence so that a photon sensing detector records the reduced light level and activates an appropriate alarm or indicator.

Inventors:

Partin, Judy K ^[1]; Ward, Thomas E ^[1]; Grey, Alan E ^[1]

Idaho Falls, ID

Issue Date:: 1992-01-01

Research Org.:: EG & G IDAHO INC

OSTI Identifier:: 868142

Patent Number(s):: 5082630

Assignee:: United States of America as represented by United States (Washington, DC)

Patent Classifications (CPCs):: G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES

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G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
G01N2021/6434 - {Optrodes}
G01N2021/7736 - {exposed, cladding free}
G01N2021/7786 - {Fluorescence}
G01N21/6428 - {Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
G01N21/648 - {using evanescent coupling or surface plasmon coupling for the excitation of fluorescence}
G01N21/7703 - {using reagent-clad optical fibres or optical waveguides
G01N2201/0221 - Portable
G01N33/54373 - {involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings}
G01N33/946 - {CNS-stimulants, e.g. cocaine, amphetamines}
G01N33/9486 - {Analgesics, e.g. opiates, aspirine}

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DOE Contract Number:: AC07-76ID01570

Resource Type:: Patent

Country of Publication:: United States

Language:: English

Subject:: fiber; optic; detector; immuno-testing; portable; senses; presence; specific; target; chemicals; air; gas; exchanging; chemical; fluoroescently-tagged; antigen; bound; antibody; attached; optical; replacing; fluorescently-tagged; reduces; fluorescence; photon; sensing; records; reduced; light; level; activates; appropriate; alarm; indicator; fiber optic; optical fiber; target chemical; sensing detector; specific target; optic detector; target chemicals; portable fiber; light level; /422/356/436/

Citation Formats


                    Partin, Judy K, Ward, Thomas E, and Grey, Alan E. Fiber optic detector for immuno-testing.  United States: N. p., 1992. 
        Web.

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                    Partin, Judy K, Ward, Thomas E, & Grey, Alan E. Fiber optic detector for immuno-testing.  United States.

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                    Partin, Judy K, Ward, Thomas E, and Grey, Alan E. Wed .  
        "Fiber optic detector for immuno-testing".  United States.  https://www.osti.gov/servlets/purl/868142.

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@article{osti_868142,

  title        = {Fiber optic detector for immuno-testing},

  author       = {Partin, Judy K and Ward, Thomas E and Grey, Alan E},

  abstractNote = {A portable fiber optic detector that senses the presence of specific target chemicals in air or a gas by exchanging the target chemical for a fluoroescently-tagged antigen that is bound to an antibody which is in turn attached to an optical fiber. Replacing the fluorescently-tagged antigen reduces the fluorescence so that a photon sensing detector records the reduced light level and activates an appropriate alarm or indicator.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {1992},

  month        = {1}

}

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