Method and apparatus for continuous electrophoresis
Abstract
A method and apparatus for conducting continuous separation of substances by electrophoresis are disclosed. The process involves electrophoretic separation combined with couette flow in a thin volume defined by opposing surfaces. By alternating the polarity of the applied potential and producing reciprocating short rotations of at least one of the surfaces relative to the other, small increments of separation accumulate to cause substantial, useful segregation of electrophoretically separable components in a continuous flow system.
- Inventors:
-
- Knoxville, TN
- Issue Date:
- Research Org.:
- Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
- OSTI Identifier:
- 868137
- Patent Number(s):
- 5082541
- Assignee:
- United States of America as represented by United States (Washington, DC)
- Patent Classifications (CPCs):
-
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01D - SEPARATION
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- AC05-84OR21400
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- method; apparatus; continuous; electrophoresis; conducting; separation; substances; disclosed; process; involves; electrophoretic; combined; couette; flow; volume; defined; opposing; surfaces; alternating; polarity; applied; potential; producing; reciprocating; rotations; relative; increments; accumulate; substantial; useful; segregation; electrophoretically; separable; components; volume defined; continuous flow; process involves; opposing surfaces; applied potential; separable components; opposing surface; continuous separation; electrophoretic separation; /204/
Citation Formats
Watson, Jack S. Method and apparatus for continuous electrophoresis. United States: N. p., 1992.
Web.
Watson, Jack S. Method and apparatus for continuous electrophoresis. United States.
Watson, Jack S. Wed .
"Method and apparatus for continuous electrophoresis". United States. https://www.osti.gov/servlets/purl/868137.
@article{osti_868137,
title = {Method and apparatus for continuous electrophoresis},
author = {Watson, Jack S},
abstractNote = {A method and apparatus for conducting continuous separation of substances by electrophoresis are disclosed. The process involves electrophoretic separation combined with couette flow in a thin volume defined by opposing surfaces. By alternating the polarity of the applied potential and producing reciprocating short rotations of at least one of the surfaces relative to the other, small increments of separation accumulate to cause substantial, useful segregation of electrophoretically separable components in a continuous flow system.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1992},
month = {1}
}
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Works referenced in this record:
Velocity Gradient Stabilised, Continuous, Free Flow Electrophoresis. A Review
journal, January 1980
- Mattock, Patrick; Aitchison, Gordon F.; Thomson, Alan R.
- Separation and Purification Methods, Vol. 9, Issue 1