Imaging agents for in vivo magnetic resonance and scintigraphic imaging

Engelstad, Barry L; Raymond, Kenneth N; Huberty, John P; White, David L

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Title: Imaging agents for in vivo magnetic resonance and scintigraphic imaging

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Abstract

Methods are provided for in vivo magnetic resonance imaging and/or scintigraphic imaging of a subject using chelated transition metal and lanthanide metal complexes. Novel ligands for these complexes are provided.

Inventors:

Engelstad, Barry L ^[1]; Raymond, Kenneth N ^[2]; Huberty, John P ^[3]; White, David L ^[4]

Orinda, CA
Berkeley, CA
Corte Madera, CA
Oakland, CA

Issue Date:: Tue Jan 01 00:00:00 EST 1991

Research Org.:: Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)

OSTI Identifier:: 867790

Patent Number(s):: 5010191

Assignee:: Regents of University of California (Oakland, CA)

Patent Classifications (CPCs):: A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07D - HETEROCYCLIC COMPOUNDS

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A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
A61K2123/00 - Preparations for testing in vivo
A61K49/103 - {the complex-forming compound being acyclic, e.g. DTPA}
A61K51/0478 - {complexes from non-cyclic ligands, e.g. EDTA, MAG3}

C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07D - HETEROCYCLIC COMPOUNDS
C07D241/08 - with oxygen atoms directly attached to ring carbon atoms

C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07F - ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
C07F15/025 - {without a metal-carbon linkage}
C07F5/003 - {without C-Metal linkages}

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DOE Contract Number:: AC03-76SF00098

Resource Type:: Patent

Country of Publication:: United States

Language:: English

Subject:: imaging; agents; vivo; magnetic; resonance; scintigraphic; methods; provided; subject; chelated; transition; metal; lanthanide; complexes; novel; ligands; resonance imaging; imaging agents; metal complexes; magnetic resonance; transition metal; metal complex; novel ligands; imaging agent; imaging method; scintigraphic imaging; vivo magnetic; lanthanide metal; /999/

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                    Engelstad, Barry L, Raymond, Kenneth N, Huberty, John P, and White, David L. Imaging agents for in vivo magnetic resonance and scintigraphic imaging.  United States: N. p., 1991. 
        Web.

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                    Engelstad, Barry L, Raymond, Kenneth N, Huberty, John P, & White, David L. Imaging agents for in vivo magnetic resonance and scintigraphic imaging.  United States.

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                    Engelstad, Barry L, Raymond, Kenneth N, Huberty, John P, and White, David L. Tue .  
        "Imaging agents for in vivo magnetic resonance and scintigraphic imaging".  United States.  https://www.osti.gov/servlets/purl/867790.

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@article{osti_867790,

  title        = {Imaging agents for in vivo magnetic resonance and scintigraphic imaging},

  author       = {Engelstad, Barry L and Raymond, Kenneth N and Huberty, John P and White, David L},

  abstractNote = {Methods are provided for in vivo magnetic resonance imaging and/or scintigraphic imaging of a subject using chelated transition metal and lanthanide metal complexes. Novel ligands for these complexes are provided.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {Tue Jan 01 00:00:00 EST 1991},

  month        = {Tue Jan 01 00:00:00 EST 1991}

}

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