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Title: Ethanol production by Escherichia coli strains co-expressing Zymomonas PDC and ADH genes

Abstract

A novel operon and plasmids comprising genes which code for the alcohol dehydrogenase and pyruvate decarboxylase activities of Zymomonas mobilis are described. Also disclosed are methods for increasing the growth of microorganisms or eukaryotic cells and methods for reducing the accumulation of undesirable metabolic products in the growth medium of microorganisms or cells.

Inventors:
 [1];  [2];  [1]
  1. Gainesville, FL
  2. Lincoln, NE
Issue Date:
Research Org.:
Univ. of Florida, Gainesville, FL (United States)
OSTI Identifier:
867740
Patent Number(s):
5000000
Assignee:
University of Florida (Gainesville, FL)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
DOE Contract Number:  
FG05-86ER13574
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
ethanol; production; escherichia; coli; strains; co-expressing; zymomonas; pdc; adh; genes; novel; operon; plasmids; comprising; code; alcohol; dehydrogenase; pyruvate; decarboxylase; activities; mobilis; described; disclosed; methods; increasing; growth; microorganisms; eukaryotic; cells; reducing; accumulation; undesirable; metabolic; products; medium; comprising genes; plasmids comprising; zymomonas mobilis; ethanol production; alcohol dehydrogenase; pyruvate decarboxylase; undesirable metabolic; metabolic products; growth medium; escherichia coli; coli strain; /435/

Citation Formats

Ingram, Lonnie O, Conway, Tyrrell, and Alterthum, Flavio. Ethanol production by Escherichia coli strains co-expressing Zymomonas PDC and ADH genes. United States: N. p., 1991. Web.
Ingram, Lonnie O, Conway, Tyrrell, & Alterthum, Flavio. Ethanol production by Escherichia coli strains co-expressing Zymomonas PDC and ADH genes. United States.
Ingram, Lonnie O, Conway, Tyrrell, and Alterthum, Flavio. Tue . "Ethanol production by Escherichia coli strains co-expressing Zymomonas PDC and ADH genes". United States. https://www.osti.gov/servlets/purl/867740.
@article{osti_867740,
title = {Ethanol production by Escherichia coli strains co-expressing Zymomonas PDC and ADH genes},
author = {Ingram, Lonnie O and Conway, Tyrrell and Alterthum, Flavio},
abstractNote = {A novel operon and plasmids comprising genes which code for the alcohol dehydrogenase and pyruvate decarboxylase activities of Zymomonas mobilis are described. Also disclosed are methods for increasing the growth of microorganisms or eukaryotic cells and methods for reducing the accumulation of undesirable metabolic products in the growth medium of microorganisms or cells.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Jan 01 00:00:00 EST 1991},
month = {Tue Jan 01 00:00:00 EST 1991}
}